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Record W2028463594 · doi:10.2135/cropsci2012.09.0526

Genomic, Marker‐Assisted, and Pedigree‐BLUP Selection Methods for β‐Glucan Concentration in Elite Oat

2013· article· en· W2028463594 on OpenAlexaff
Franco G. Asoro, Mark A. Newell, William D. Beavis, M. Paul Scott, Nicholas A. Tinker, Jean‐Luc Jannink

Bibliographic record

VenueCrop Science · 2013
Typearticle
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicGenetic Mapping and Diversity in Plants and Animals
Canadian institutionsAgriculture and Agri-Food Canada
FundersNational Institute of Food and AgricultureU.S. Department of Agriculture
KeywordsBiologyBest linear unbiased predictionSelection (genetic algorithm)AvenaMarker-assisted selectionGenomic selectionQuantitative trait locusBiotechnologyGeneticsGenotypeAgronomyGeneSingle-nucleotide polymorphism

Abstract

fetched live from OpenAlex

ABSTRACT β‐glucan, a soluble fiber found in oat (Avena sativa L.) grain, is good for human health, and selection for higher levels of this compound is regarded as an important breeding objective. Recent advances in oat DNA markers present an opportunity to investigate new selection methods for polygenic traits such as β‐glucan concentration. Our objectives in this study were to compare genomic, marker‐assisted, and best linear unbiased prediction (BLUP)–based phenotypic selection for short‐term response to selection and ability to maintain genetic variance for β‐glucan concentration. Starting with a collection of 446 elite oat lines from North America, each method was conducted for two cycles. The average β‐glucan concentration increased from 4.57 g/100 g in Cycle 0 to between 6.66 and 6.88 g/100 g over the two cycles. The averages of marker‐based selection methods in Cycle 2 were greater than those of phenotypic selection (P < 0.08). Progenies with the highest β‐glucan came from the marker‐based selection methods. Marker‐assisted selection (MAS) for higher β‐glucan concentration resulted in a later heading date. We also found that marker‐based selection methods maintained greater genetic variance than did BLUP phenotypic selection, potentially enabling greater future selection gains. Overall, the results of these experiments suggest that genomic selection is a superior method for selecting a polygenic complex trait like β‐glucan concentration.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.001
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.002
Threshold uncertainty score0.007

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0010.001
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.018
GPT teacher head0.300
Teacher spread0.281 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations96
Published2013
Admission routes1
Has abstractyes

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