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Record W2028463594 · doi:10.2135/cropsci2012.09.0526

Genomic, Marker‐Assisted, and Pedigree‐BLUP Selection Methods for β‐Glucan Concentration in Elite Oat

2013· article· en· W2028463594 on OpenAlex

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

affAt least one author lists a Canadian institution in the pinned OpenAlex snapshot.

Bibliographic record

VenueCrop Science · 2013
Typearticle
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicGenetic Mapping and Diversity in Plants and Animals
Canadian institutionsAgriculture and Agri-Food Canada
FundersNational Institute of Food and AgricultureU.S. Department of Agriculture
KeywordsBiologyBest linear unbiased predictionSelection (genetic algorithm)AvenaMarker-assisted selectionGenomic selectionQuantitative trait locusBiotechnologyGeneticsGenotypeAgronomyGeneSingle-nucleotide polymorphism

Abstract

fetched live from OpenAlex

ABSTRACT β‐glucan, a soluble fiber found in oat ( Avena sativa L.) grain, is good for human health, and selection for higher levels of this compound is regarded as an important breeding objective. Recent advances in oat DNA markers present an opportunity to investigate new selection methods for polygenic traits such as β‐glucan concentration. Our objectives in this study were to compare genomic, marker‐assisted, and best linear unbiased prediction (BLUP)–based phenotypic selection for short‐term response to selection and ability to maintain genetic variance for β‐glucan concentration. Starting with a collection of 446 elite oat lines from North America, each method was conducted for two cycles. The average β‐glucan concentration increased from 4.57 g/100 g in Cycle 0 to between 6.66 and 6.88 g/100 g over the two cycles. The averages of marker‐based selection methods in Cycle 2 were greater than those of phenotypic selection ( P < 0.08). Progenies with the highest β‐glucan came from the marker‐based selection methods. Marker‐assisted selection (MAS) for higher β‐glucan concentration resulted in a later heading date. We also found that marker‐based selection methods maintained greater genetic variance than did BLUP phenotypic selection, potentially enabling greater future selection gains. Overall, the results of these experiments suggest that genomic selection is a superior method for selecting a polygenic complex trait like β‐glucan concentration.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.772
Threshold uncertainty score0.241

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.018
GPT teacher head0.300
Teacher spread0.281 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it