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Clinical Issues and Treatment of Lung Cancer in Mexico

2012· article· en· W2029899146 on OpenAlexvenueno aff
Rufino Echegoyen-Carmona, Daniel Mendoza-Posada, Catalina Camacho-Mendoza, Oswaldo Rafael Sánchez-Campos

Bibliographic record

VenueJournal of Analytical Oncology · 2012
Typearticle
Languageen
FieldMedicine
TopicLung Cancer Diagnosis and Treatment
Canadian institutionsnot available
Fundersnot available
KeywordsMedicineLung cancerPneumonectomyGemcitabineInternal medicineChemotherapyCancerStage (stratigraphy)MetastasisFamily historyHistopathologySurgeryOncologyPathology

Abstract

fetched live from OpenAlex

Retrospective analysis of 101 lung cancer patients treated at the INER [National Respiratory Diseases Institute] in Mexico from January 2006 to October 2007. Objective: Analysis of clinical situation and treatment. Results: The study comprised 59 men and 42 women: 58 % > 60 years old. 14.8% were non-smokers or had no smoking history. 85.2% were heavy smokers with a smoking history above15 packs per year. Eleven patients had one family member with cancer. 86.1% of them were admitted to hospital when the tumor stage was between IIIA and IV. 21 patients of this group had metastasis. 86.1% had an ECOG grade of 0.2. Two analytical parameters were handled: RECIST and the media overall survival. 93 of 101 patients (92%) were treated with chemotherapy: 51 of them (54.7%) with Cisplatine and Paclitaxel, 29 (31.1%) with Cisplatine and Vinorrelbine, and 13 (13.8%) with Cisplatine and Gemcitabine, each one for 2 to 6 cycles. According to RECIST, 6 patients had a complete response, 19 had progressions with distal metastasis, and 68 had partial responses. The median overall survival was of 17.0, 18.4, and 16.1months, respectively. Chirurgic intervention was carried out in 8 patients, lobectomy in 7 patients, and one had a pneumonectomy with resection of mediastinal lymph nodes and adyuvant chemotherapy. Histopathology of the lymph nodes and bronchial section were negative for neoplasia. The disease-free survival was 13 to 25 months in lobectomies and 22 months in the pneumonectomy. The cause of dead could not be specified because they did not continue attending post-treatment control. Conclusion: Lack of Health Education amongst patients and their families was found to be a major cause which prevented a more effective result of the treatment. This study also concludes that a multidisciplinary treatment for lung cancer patients is required.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.037
Threshold uncertainty score0.254

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.057
GPT teacher head0.483
Teacher spread0.426 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

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Citations0
Published2012
Admission routes1
Has abstractyes

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