Seafood Allergy In South Africa- Studies in the Domestic and Occupational Setting
Bibliographic record
Abstract
Background: Increased consumption of seafood due to the promotion of a healthy diet and increased processing of seafood to meet these domestic consumption needs, has lead to more frequent reporting of allergic reactions. The spectrum of seafood allergy associated with domestic and occupational exposure in the South African setting was investigated. Methods/data base: In vitro studies were conducted on sera of 80 subjects reporting allergic symptoms associated with ingesting seafood. The distribution of positive immunoglobulin E (IgE) responses was evaluated (by UniCAP-RAST) as well as patterns of concurrent reactivity and cross-reactivity (by Western-blotting) to different seafood groups, commonly encountered in South Africa. The contribution of occupational factors was investigated through a postal survey of 68 seafood-processing workplaces. Results: Patterns of IgE sensitization indicate that the majority of subjects (50%) were positive to crustaceans, 30% to molluscs, and 20% to fish species. More than half of the individuals reacted to one seafood groups, 36% to two seafood groups, and 11% to all three seafood groups. The complexity of immune responses to finfish and mollusc species was evident in the different allergen profiles obtained for fresh and cooked seafood. The strongest immune response among the four tested fish species was to hake - the most common seafood processed in workplaces and therefore likely to pose an allergenic hazard to workers in the seafood processing industry. Among seafood processing factories the prevalence of work-related skin symptoms per workplace was substantially higher (0%-100%) than that for asthmatic (0%-5%) and other allergic symptoms (0%-37%). Conclusions: Our preliminary investigations into the spectrum of seafood allergy in South Africa indicate that the potential of local seafood species in causing sensitization, either through ingestion, skin contact or inhalation are important considerations when investigating seafood allergy in the domestic or occupational setting.
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How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.002 | 0.004 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.001 | 0.000 |
| Bibliometrics | 0.001 | 0.001 |
| Science and technology studies | 0.000 | 0.001 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.001 | 0.000 |
| Research integrity | 0.000 | 0.001 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".