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Record W2033442357 · doi:10.3923/ijp.2005.357.359

Is Dexamethasone a Suitable Alternative for Dihydroergotamine on Migraine Attacks?

2005· article· en· W2033442357 on OpenAlexaboutno aff
Nahid Jivad, Mahmoud Rafieian‐Kopaei

Bibliographic record

VenueInternational Journal of Pharmacology · 2005
Typearticle
Languageen
FieldMedicine
TopicMigraine and Headache Studies
Canadian institutionsnot available
Fundersnot available
KeywordsDihydroergotamineMigraineDexamethasoneMedicinePharmacologyAnesthesiaInternal medicine

Abstract

fetched live from OpenAlex

Abstract: This study was conducted to compare the effect of dexamethasone with dihydroergotamine on migraine attacks. A clinical study was carried out on 72 migraineurs, aged 15 to 55 years old. Patients who met the diagnostic criteria for migraine, as defined by the International Headache Society (HIS) were selected from the ones referred to emergency department. Patients received 1 mg dihydroergotamine (DHE) or 4 mg dexamethasone intravenously. Headache intensity was scored based on McGill method on a 1-15 point scale. Data were collected by questionnaires, which were filled on entry, 10 and 30 min after drug injections. The average frequency of migraine attacks was 2.2 per month and the duration of attacks was 12.2 h. The average score of headache intensity in start of study was 12.86. The intensity of headache 10 min after drug injection was less in both DHE and dexamethasone groups compared to the intensity of headache before drug injection (p<0.01). It was the same in both groups 30 min after injection of drugs compared to the intensity, 10 min after injection (p<0.01). There was no difference for intensity of headaches between two groups, 10 or 30 min after injection of DHE or dexamethasone. Twenty patients in DHE groups showed side effects, however, side effects was not seen in dexamethasone group. Therefore, dexamethasone seems to be a suitable alternative for ergot alkaloids in emergency migraine headaches.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesInsufficient payload (model declined to judge)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: Not applicable
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.095
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.053
GPT teacher head0.432
Teacher spread0.379 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designNot applicable
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations6
Published2005
Admission routes1
Has abstractyes

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