Incidence of Argyrophil Cells in Normal and Dysplastic Conditions of Human Uterine Cervix
Bibliographic record
Abstract
Background: Cervi cal intraepithelial neoplasia, also known as cervical dysplasia, is the potentially premalignant transformation and abnormal growth of squamous cells on the surface of the cervix. Argyrophil cells occur rarely in the normal human uterine cervix but are found in a variety of invasive tumours arising in the cervix. Methods: In this study, with the Grimelius argyrophilic reaction 317 normal uterine cervices were stained, out of which 158 cases (49.84%) were positive. And 27 dysplastic cases of uterine cervices were stained with Grimelius argyrophilic reaction, out of which 25 (92.59%) showed the argyrophilic positivity. When Normal cervix was compared with Dysplastic cervix the probability value was < 0.001 which was significantly higher. The immunomarkers used in the present study were Chromogranin A and Synaptophysin. Results: Argyrophil cells in ectocervical epithelium are rare. It is the first study which reveals the comparison of the presence of argyrophilic cells in normal and dysplastic human uterine cervix, using Grimelius argyrophilic reaction and Immunohistochemical staining using Chromogranin A and Synaptophysin as argyrophilic markers with larger sample size and higher positivity. Conclusion: From the results of our study it is clear that argyrophilia is a significant marker in dysplasia. doi: http://dx.doi.org/10.4021 /jcs116w
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How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.003 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".