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Record W2038057377 · doi:10.1021/om050574i

Intramolecular C−H and N−H Transfer by Ruthenium(II) Amidophosphine Complexes

2005· article· en· W2038057377 on OpenAlexaff
Michael D. Fryzuk, M.J. Petrella, Brian O. Patrick

Bibliographic record

VenueOrganometallics · 2005
Typearticle
Languageen
FieldChemistry
TopicAsymmetric Hydrogenation and Catalysis
Canadian institutionsUniversity of British Columbia
Fundersnot available
KeywordsChemistryDeprotonationDiastereomerLigand (biochemistry)RutheniumMedicinal chemistryIntramolecular forceStereochemistryAmine gas treatingAmideDenticityCrystallographyCrystal structureOrganic chemistryCatalysis

Abstract

fetched live from OpenAlex

The formation of ruthenium amidophosphine complexes was accomplished by the addition of [P 2 N 2 ]Li 2 (Diox) (where P 2 N 2 is PhP(CH 2 SiMe 2 NSiMe 2 CH 2 ) 2 PPh and Diox is 1,4-dioxane) to [RuCl 2 (cod)] x to generate [P 2 N 2 ]Ru(cod), or to RuCl 2 (PPh 3 ) 3 to generate [P 2 NNH]Ru(C 6 H 4 PPh 2 ). In the former complex, the Ru(II) center is in an octahedral environment perched above the P 2 N 2 macrocycle having two formally anionic amido donors; in the latter complex, there is only one amido ligand with the other as an amine donor where the proton originates from the cyclometalated triphenylphosphine group. Reaction of the tridentate amidophosphine ligand precursor [NPN]Li 2 (THF) 2 (where NPN is PhP(CH 2 SiMe 2 NPh) 2 ) with [RuCl 2 (cod)] x results in the formation of two diastereomeric complexes of the formula [NPNH]Ru(η 3:η 2 -C 8 H 11 ), wherein the cyclooctadiene ligand has been deprotonated by the ancillary ligand to generate a cyclooctadienyl unit. These Ru(II) complexes are five-coordinate with a bidentate PN ligand and a dangling amine unit. The diastereomers are in equilibrium, as shown by variable-temperature NMR studies. The fluxional process that interconverts diastereomers involves proton transfer from the dangling amine arm to the amido unit, a process that equilibrates the two ends of the tridentate NPN ligand on the chemical time scale. Deprotonation of the amine arm by MN(SiMe 3 ) 2 generates a series of ruthenate complexes of the formula [M(THF)]([NPN]Ru(η 3:η 2 -C 8 H 11 )), where M = Li or Na. Addition of Me 3 SiCl results in the formation of new diastereomers that contain silylated dangling arms, and these diastereomers do not interconvert.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesInsufficient payload (model declined to judge)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.381
Threshold uncertainty score0.995

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0060.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.004
GPT teacher head0.192
Teacher spread0.188 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations12
Published2005
Admission routes1
Has abstractyes

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