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Record W2039085793 · doi:10.1002/pri.333

Changes in gait and symptoms after bilateral pallidotomy: a client with Parkinson's disease

2006· article· en· W2039085793 on OpenAlexaff
George I. Turnbull

Bibliographic record

VenuePhysiotherapy Research International · 2006
Typearticle
Languageen
FieldMedicine
TopicParkinson's Disease Mechanisms and Treatments
Canadian institutionsDalhousie University
Fundersnot available
KeywordsPallidotomyGaitParkinson's diseasePhysical medicine and rehabilitationPhysical therapyPsychologyMedicineGait analysisDeep brain stimulationDiseaseInternal medicine

Abstract

fetched live from OpenAlex

A single-subject, time-series design was used to describe a female with young-onset Parkinson's disease who, after a period of 15 years, was demonstrating long term side effects of medication in addition to the progression of Parkinson's disease. She underwent a bilateral pallidotomy to address these problems. Prior to her surgery, her spatiotemporal gait kinematics were measured at intervals before and after medication ingestion. The identical procedures were undertaken one month and at four months post-pallidotomy. In all three sessions, the Webster Scale scored her symptoms while her medication was not working (Off) and again when effective (On). After surgery, she was interviewed to obtain a qualitative impression of the outcome. Before the surgery, the gait parameters demonstrated a fluctuating profile. Forty-five minutes post-medication, her gait parameters approached normal levels but significant dyskinetic movements were evident. Her Webster Scale scores indicated advanced Parkinson's disease particularly when Off One-month post-pallidotomy, her gait parameters were more consistent with dyskinesias mildly present. Her Webster Scale scores were reduced while both Off and On. Four months post-pallidotomy her gait parameters were entirely consistent and within normal limits. Her Webster Scale scores were the same Off and On and no dyskinesias were detectable. The excellent result was probably enhanced by the patient's dedication to regular exercise designed to minimize secondary physical complications.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.040
Threshold uncertainty score0.501

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.019
GPT teacher head0.343
Teacher spread0.324 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2006
Admission routes1
Has abstractyes

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