Observation of nonlinear shear wave propagation using magnetic resonance elastography
Bibliographic record
Abstract
MR elastography (MRE) is an MRI modality that is increasingly being used to image tissue elasticity throughout the body. One MRE technique that has received a great deal of attention is based on visualizing shear waves, which reveal stiffness by virtue of their local wavelength. However, the shape of propagating shear waves can also provide valuable information about the nonlinear stress-strain behavior of tissue. Here an experiment is proposed that allows the observation of nonlinear wave propagation based on spatial-temporal phase contrast images. A theoretical description of the wave propagation was developed that reflects typical MRE excitation, which involves excitation modes both parallel and perpendicular to B0. Based on this model, it is shown that both odd and even higher harmonics are produced with their amplitudes dependent on the details of the actuator, imaging geometry, and the nonlinear tissue properties. With appropriate motion encoding, harmonic vibrations arising from nonlinear tissue response can be detected. The effect is demonstrated on an agarose gel phantom using a sinusoidal shear vibration of 150 Hz, and clearly shows the presence of harmonics at 600 and 750 Hz. Using an estimate of the strain energy of the phantom, we were able to determine the nonlinear tissue properties.
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How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.001 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.001 | 0.000 |
| Bibliometrics | 0.001 | 0.002 |
| Science and technology studies | 0.000 | 0.001 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".