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Record W2041812621 · doi:10.1021/om700502k

Synthesis and Structural Characterization of η<sup>6</sup>-Arene Ruthenium Complexes Bearing Pentadienyl and Oxopentadienyl Ligands

2007· article· en· W2041812621 on OpenAlexafffund
A. Ramírez-Monroy, M. Angeles Paz‐Sandoval, Michael J. Ferguson, Jeffrey M. Stryker

Bibliographic record

VenueOrganometallics · 2007
Typearticle
Languageen
FieldChemistry
TopicOrganometallic Complex Synthesis and Catalysis
Canadian institutionsUniversity of Alberta
FundersUniversity of Alberta
KeywordsChemistryRutheniumMedicinal chemistryYield (engineering)MethanolTrimethylsilylCationic polymerizationDicationDiastereomerStereochemistryCatalysisPolymer chemistryMoleculeOrganic chemistry

Abstract

fetched live from OpenAlex

General methodology for the synthesis of cationic ruthenium(II) η 5 -pentadienyl compounds stabilized by the (η 6 -C 6 Me 6 )Ru fragment has been developed. Pentadienyl compounds [(η 6 -C 6 Me 6 )Ru{η 5 -CH 2 C(R 2 )CHC(R 4 )CH(R 5 )}]BF 4 (R 2 = R 4 = R 5 = H, 2 -BF 4; R 2, R 4 = H, R 5 = Me, 3; R 2, R 4 = Me, R 5 = H, 4 ) can be prepared in good yields from reactions of the labile dication [(η 6 -C 6 Me 6 )Ru(acetone) 3 ](BF 4 ) 2 ( 1 ) with 1-trimethylsilyl-2,4-pentadiene, 1-trimethylsilyl-2,4-hexadiene, and 2,4-dimethyl-1-trimethylstannyl-2,4-pentadiene, respectively. Compound 3 is isolated in 90% yield as a mixture of the syn and anti isomers. In contrast, the reaction of pentadienyllithium with [(η 6 -C 6 Me 6 )RuCl 2 ] 2 provides a nonselective reaction, which affords a mixture of isomeric η 1 -, η 3 -, and η 5 -coordinated pentadienyl complexes, [(η 6 -C 6 Me 6 )Ru(η 5 -CH 2 CHCHCHCH 2 )]Cl ( 2 -Cl), [(η 6 -C 6 Me 6 )Ru(η 3 -CH 2 CHCHCH CH 2 )Cl] ( 5 ), and [(η 6 -C 6 Me 6 )Ru(η 1 -CH 2 CH CHCH CH 2 )Cl] 2 ( 6 ); the reaction of 1,4-pentadiene and [(η 6 -C 6 Me 6 )RuCl 2 ] 2 in ethanolic carbonate similarly gives a mixture containing complex 5, [(η 6 -C 6 Me 6 )Ru{η 3 -C(Me)CHC(Me)}Cl] ( 7 ), and [(η 6 -C 6 Me 6 )Ru(η 3 -CH 2 CHCHCH 2 Me)Cl] ( 8 ). Using a similar strategy for the synthesis of the corresponding oxopentadienyl derivatives is much more complicated, even when using an enol silane as the nucleophilic precursor, reflecting a greater competition among alternative bonding modes for the oxopentadienyl derivatives compared to the corresponding pentadienyl analogues. The reaction of lithium oxopentadienide and [(η 6 -C 6 Me 6 )RuCl 2 ] 2 in THF affords [(η 6 -C 6 Me 6 )Ru(η 3 - exo - syn -CH 2 C(Me)CHC(Me)O)Cl] ( 11 ) in poor yield, although this complex readily affords [(η 6 -C 6 Me 6 )Ru(η 5 -CH 2 C(Me)CHC(Me)O)]BF 4 ( 9 ) upon reaction with silver tetrafluoroborate. The analogous η 6 -benzene complex, [(η 6 -C 6 H 6 )Ru(η 3 - exo - syn -CH 2 C(Me)CHC(Me)O)Cl] ( 13 ), can be prepared, albeit in very low yield, in an analogous manner to that reported for complex 11, along with traces of an isomeric congener, 13 - endo . The use of 1-trimethylsilyloxy-1,3-butadiene unexpectedly provided strongly contrasting results upon addition to dicationic complex 1, returning a mixture of η 5 - and η 3 -oxopentadienyl complexes [(η 6 -C 6 Me 6 )Ru(η 5 -CH 2 CHCHCHO)]BF 4 ( 14 ) and [(η 6 -C 6 Me 6 )Ru(1−3,5-η- exo-syn -CH 2 CHCHCHO)] 2 (BF 4 ) 2 ( 15 ). Addition of water to the dimeric product 15 affords the monomeric aquo adduct [(η 6 -C 6 Me 6 )Ru(η 3 - exo-syn- CH 2 CHCHCHO)(H 2 O)]BF 4 ( 16 ), but this complex is unstable toward isolation, reverting back to dimer 15 upon precipitation. A more stable adduct, [(η 6 -C 6 Me 6 )Ru(η 3 - exo - syn- CH 2 CHCHCHO)(MeCN)]BF 4 ( 17 ), is isolated upon dissolution in acetonitrile, and addition of aqueous NaCl to 15 gives compound [(η 6 -C 6 Me 6 )Ru(η 3 - exo - syn- CH 2 CHCHCHO)Cl] ( 20 ). Compound 14 affords the decarbonylation product [(η 6 -C 6 Me 6 )Ru(η 3 -allyl)(CO)]BF 4 ( 19 ) as a mixture of exo and endo allyl isomers. The solid-state structures for compounds 2 -BF 4, 4, 9, 11, 13, 15, and 19- exo, as determined by X-ray crystallography, are also reported.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow), Insufficient payload (model declined to judge)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.079
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0060.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.012
GPT teacher head0.218
Teacher spread0.206 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations14
Published2007
Admission routes2
Has abstractyes

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