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Record W2042095417 · doi:10.1055/s-2009-1216483

Shikimic Acid as a Marker Compound from Ludwigia alternifolia L.

2009· article· en· W2042095417 on OpenAlexfundno aff
AS Rao, TJ Smillie, IA Khan

Bibliographic record

VenuePlanta Medica · 2009
Typearticle
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicPlant biochemistry and biosynthesis
Canadian institutionsnot available
FundersNational Institute on Drug AbuseAgricultural Research ServiceNational Center for Complementary and Alternative MedicineNational Oceanic and Atmospheric AdministrationU.S. Food and Drug AdministrationNational Science Foundation of Sri LankaUniversity of ColomboUniversity Grants CommissionTata TrustsInternational Science CouncilKurukshetra UniversityChina Academy of Traditional Chinese MedicineWestern Carolina UniversityUniversity of British ColumbiaDeutsche KrebshilfeNational Natural Science Foundation of ChinaNational Institutes of HealthTürkiye Bilimsel ve Teknolojik Araştırma KurumuHong Kong Polytechnic UniversityChinese Academy of SciencesWake Forest University
KeywordsShikimic acidBiologyBotanyChemistryStereochemistryBiochemistry

Abstract

fetched live from OpenAlex

Ludwigia alternifolia L belongs to the Onagraceae family and is distributed throughout the Northeast, Midwest and Southern US. Shikimic acid (Fig. 1) was first isolated in 1885 by Eijkman from the fruit of the Japanese plant Illicium religiosum Sieb [1]. The elucidation of its structure nearly 50 years later [2,3] and the discovery that shikimic acid was found to play an important role in the biosynthesis of the three aromatic amino acids phenylalanine, tyrosine, and tryptophan [4] resulted in an intensified research effort towards its synthesis [5–9], isolation from other organisms [10], identification of its metabolites [11,12] and its transformation into potential chemotherapeutics. This latter area of research has lead to the syntheses of various bioactive compounds from shikimic acid. The research outlined in this presentation is the first report for the isolation of shikimic acid from this plant.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.084
Threshold uncertainty score0.779

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.007
GPT teacher head0.226
Teacher spread0.219 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2009
Admission routes1
Has abstractyes

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