A simple risk index accurately predicted mortality in patients with ST elevation myocardial infarction
Bibliographic record
Abstract
Morrow DA, Antman EM, Giugliano RP, et al. A simple risk index for rapid initial triage of patients with ST-elevation myocardial infarction: an InTIME II substudy. Lancet2001 Nov 10; 358 : 1571 –5 [OpenUrl][1][CrossRef][2][PubMed][3][Web of Science][4] QUESTION: Can a simple risk index based on 3 routinely collected variables accurately predict mortality in patients with ST elevation myocardial infarction (MI)? Patient data from 3 multicentre randomised controlled trials were used for the development and validation of a risk index (Intravenous nPA for the Treatment of Infarcting Myocardium Early [InTIME II] Trial; and Thrombolysis and Thrombin Inhibition in Myocardial Infarction [TIMI] 9A and B trials). >800 hospitals worldwide from the InTIME II trial for index development and {150 centres in the US, UK, Canada, Israel, and Germany}* from the TIMI 9A and B trials for index validation. The development set comprised data from 13 253 patients who had ST elevation MI and were enrolled within 6 hours of symptom onset, and who did not have a history of cerebrovascular disease, systolic blood pressure (SBP) … [1]: {openurl}?query=rft.jtitle%253DLancet%26rft.stitle%253DLancet%26rft.aulast%253DMorrow%26rft.auinit1%253DD.%2BA.%26rft.volume%253D358%26rft.issue%253D9293%26rft.spage%253D1571%26rft.epage%253D1575%26rft.atitle%253DA%2Bsimple%2Brisk%2Bindex%2Bfor%2Brapid%2Binitial%2Btriage%2Bof%2Bpatients%2Bwith%2BST-elevation%2Bmyocardial%2Binfarction%253A%2Ban%2BInTIME%2BII%2Bsubstudy.%26rft_id%253Dinfo%253Adoi%252F10.1016%252FS0140-6736%252801%252906649-1%26rft_id%253Dinfo%253Apmid%252F11716882%26rft.genre%253Darticle%26rft_val_fmt%253Dinfo%253Aofi%252Ffmt%253Akev%253Amtx%253Ajournal%26ctx_ver%253DZ39.88-2004%26url_ver%253DZ39.88-2004%26url_ctx_fmt%253Dinfo%253Aofi%252Ffmt%253Akev%253Amtx%253Actx [2]: /lookup/external-ref?access_num=10.1016/S0140-6736(01)06649-1&link_type=DOI [3]: /lookup/external-ref?access_num=11716882&link_type=MED&atom=%2Febnurs%2F5%2F3%2F90.atom [4]: /lookup/external-ref?access_num=000172188300009&link_type=ISI
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.001 | 0.011 |
| Meta-epidemiology (narrow) | 0.001 | 0.000 |
| Meta-epidemiology (broad) | 0.001 | 0.001 |
| Bibliometrics | 0.001 | 0.001 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.001 | 0.001 |
| Open science | 0.000 | 0.001 |
| Research integrity | 0.001 | 0.001 |
| Insufficient payload (model declined to judge) | 0.002 | 0.001 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".