A simple risk index accurately predicted mortality in patients with ST elevation myocardial infarction
Bibliographic record
Abstract
Morrow DA, Antman EM, Giugliano RP, et al. A simple risk index for rapid initial triage of patients with ST-elevation myocardial infarction: an InTIME II substudy. Lancet2001 Nov 10; 358 : 1571 –5 [OpenUrl][1][CrossRef][2][PubMed][3][Web of Science][4] QUESTION: Can a simple risk index based on 3 routinely collected variables accurately predict mortality in patients with ST elevation myocardial infarction (MI)? Patient data from 3 multicentre randomised controlled trials were used for the development and validation of a risk index (Intravenous nPA for the Treatment of Infarcting Myocardium Early [InTIME II] Trial; and Thrombolysis and Thrombin Inhibition in Myocardial Infarction [TIMI] 9A and B trials). >800 hospitals worldwide from the InTIME II trial for index development and {150 centres in the US, UK, Canada, Israel, and Germany}* from the TIMI 9A and B trials for index validation. The development set comprised data from 13 253 patients who had ST elevation MI and were enrolled within 6 hours of symptom onset, and who did not have a history of cerebrovascular disease, systolic blood pressure (SBP) … [1]: {openurl}?query=rft.jtitle%253DLancet%26rft.stitle%253DLancet%26rft.aulast%253DMorrow%26rft.auinit1%253DD.%2BA.%26rft.volume%253D358%26rft.issue%253D9293%26rft.spage%253D1571%26rft.epage%253D1575%26rft.atitle%253DA%2Bsimple%2Brisk%2Bindex%2Bfor%2Brapid%2Binitial%2Btriage%2Bof%2Bpatients%2Bwith%2BST-elevation%2Bmyocardial%2Binfarction%253A%2Ban%2BInTIME%2BII%2Bsubstudy.%26rft_id%253Dinfo%253Adoi%252F10.1016%252FS0140-6736%252801%252906649-1%26rft_id%253Dinfo%253Apmid%252F11716882%26rft.genre%253Darticle%26rft_val_fmt%253Dinfo%253Aofi%252Ffmt%253Akev%253Amtx%253Ajournal%26ctx_ver%253DZ39.88-2004%26url_ver%253DZ39.88-2004%26url_ctx_fmt%253Dinfo%253Aofi%252Ffmt%253Akev%253Amtx%253Actx [2]: /lookup/external-ref?access_num=10.1016/S0140-6736(01)06649-1&link_type=DOI [3]: /lookup/external-ref?access_num=11716882&link_type=MED&atom=%2Febnurs%2F5%2F3%2F90.atom [4]: /lookup/external-ref?access_num=000172188300009&link_type=ISI
Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.
How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.001 | 0.000 |
| Bibliometrics | 0.000 | 0.001 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.001 | 0.002 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".