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Effects of Ephedrine, Caffeine, and Their Combination on Muscular Endurance

2003· article· en· W2048333718 on OpenAlexaff
Ira Jacobs, Harley Pasternak, Douglas G. Bell

Bibliographic record

VenueMedicine & Science in Sports & Exercise · 2003
Typearticle
Languageen
FieldMedicine
TopicPharmacology and Obesity Treatment
Canadian institutionsUniversity of TorontoDefence Research and Development Canada
Fundersnot available
KeywordsEphedrineBench pressPlaceboCaffeineMedicineIngestionAnalysis of varianceBlood pressureAnimal scienceInternal medicineAnesthesiaResistance training

Abstract

fetched live from OpenAlex

PURPOSE: The purpose of this study was to investigate the effects of ingesting caffeine (C), ephedrine (E), and their combination on muscular endurance, using a double-blind, repeated measures design. METHODS: Ninety minutes after ingesting either C (4 mg x kg-1), E (0.8 mg x kg-1), a combination of C+E, or a placebo (P), 13 male subjects performed a weight-training circuit consisting of three supersets (SS), each SS consisting of leg press (at 80% of 1 RM to exhaustion) followed by bench press (at 70% 1-RM to exhaustion); 2 min of rest intervened between SS. RESULTS: The trials involving ephedrine ingestion (C+E and E), when compared with the nonephedrine trials (C and P), caused significant increases (P < 0.05) in the mean number of repetitions completed for both the leg-press and bench-press exercises but only during the first SS. During that first set, the mean number (+/-SD) of repetitions for leg press was 19 +/- 8, 16 +/- 7, 14 +/- 6, and 13 +/- 5 for the C+E, E, C, and P trials, respectively. The mean numbers of repetitions for the first set of bench-press exercise were 14 +/- 3, 13 +/- 3, 12 +/- 3, and 12 +/- 3 for the C+E, E, C, and P trials, respectively. As a result, the total weight lifted during all three sets was greater for the trials involving ephedrine ingestion. Systolic blood pressure before exercise was significantly increased with both ephedrine treatment trials when compared with the other trials (C+E = 156 +/- 29 mm Hg; E = 150 +/- 14; C = 141 +/- 16; P = 138 +/- 14). CONCLUSION: It was concluded that acute ingestion of C+E and E increases muscular endurance during the first set of traditional resistance-training exercise. The performance enhancement was attributed primarily to the effects of E; there was no additive effect of C.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.001
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Non-randomized trial · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.001
Threshold uncertainty score0.003

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.008
GPT teacher head0.273
Teacher spread0.265 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designNon-randomized trial
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations92
Published2003
Admission routes1
Has abstractyes

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