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Record W2049514505 · doi:10.1177/0194599811416318a222

Middle Ear Ventilation in Children with Primary Ciliary Dyskinesia

2011· article· en· W2049514505 on OpenAlexaff
Nikolaus E. Wolter, Sharon Dell, Adrian L. James, Paolo Campisi

Bibliographic record

VenueOtolaryngology · 2011
Typearticle
Languageen
FieldMedicine
TopicCystic Fibrosis Research Advances
Canadian institutionsSickKids FoundationHospital for Sick ChildrenUniversity of Toronto
Fundersnot available
KeywordsPrimary ciliary dyskinesiaMedicineMedical recordTertiary careRetrospective cohort studyPrimary careSurgeryPediatricsAnesthesiaLungInternal medicine

Abstract

fetched live from OpenAlex

Objective 1) To review the otological presentation of children with primary ciliary dyskinesia (PCD) treated medically and surgically. 2) To compare the audiological outcomes and complications of surgical management to medical management in children with PCD. Method A retrospective chart review was performed of all patients with PCD and OME presenting to a specialized clinic at a tertiary‐quaternary care hospital from 1991 to 2009. Patients were grouped into “medical management” and “ventilation tube (VT) insertion” groups to observe changes in hearing and postoperative complications. Results Of 32 patients with PCD and OME, 20 received VTs, and 12 were treated by medical management strategies. A median of one set of VTs (range, 1‐7) were inserted per patient. Audiometric pure tone averages improved from 28.1dB to 21.6 dB ( P =. 036) following VTs, whereas patients managed medically had stable thresholds from 22.7dB to 23.6 dB ( P =. 307). At least one episode of postoperative otorrhea occurred in 9 (40%) VT insertion patients during the study period, and four had multiple episodes. Otorrhea was well controlled with medical therapy with only one requiring tube removal. Conclusion Our data supports the use of VT insertion as an option for patients with PCD and OME with mild to moderate hearing loss. Patients should be counseled on the possibility of multiple insertions and the likelihood of postoperative otorrhea, although this was not a major problem in our study group.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.009
Threshold uncertainty score0.398

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.021
GPT teacher head0.249
Teacher spread0.227 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations2
Published2011
Admission routes1
Has abstractyes

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