Acupuncture for the Treatment of HIV-Associated Acute Inflammatory Demyelinating Polyradiculoneuropathy (Guillain-Barré Syndrome)
Bibliographic record
Abstract
Background: Guillain-Barré syndrome (GBS) can be associated with human immunodeficiency virus (HIV) infection. Treatment with acupuncture may modulate immune function and restore sensation and motor function to affected areas. Objective: To describe an HIV-positive patient with GBS who received acupuncture treatment for amelioration of GBS symptoms. Design, Setting, and Patient: The patient was diagnosed with HIV infection in 1989. In January 1999 at age 40 years, he experienced a 3-week progression to nadir of bilateral paresthesias and motor impairment that ascended to the chest and then to the head, causing palpitations, partial ophthalmoplegia, and impaired taste sensation. Intervention: Initial acupuncture at bilateral points GB 34, GB 39, PC 6, and KI 3 (addition of GV 4, GV 3, BL 23, and BL 40 later) for 30 minutes each. Main Outcome Measure: Improvement in sensation and motor function as well as related GBS symptoms. Results: After 2 acupuncture treatments, the patient reported increased sensation in his feet as well as improved coordination, balance, and confidence in mobility. After 4 treatments, he reported dramatic improvement in sensation. With each subsequent treatment, the patient reported increasing energy and self-confidence. At 3 months, he reported that total recovery was approximately 75%. The most significant change was dramatic improvement in toe flexion, ankle extension, and sensation in his feet. After 1 year of treatment, the patient reported an overall total subjective recovery of 90%, including an absence of motor and sensory impairments. Conclusions: In this HIV-positive patient, acupuncture appears to have dramatically accelerated recovery from GBS, allowing greater mobility, self-confidence, social functioning, and overall quality of life. Further investigation into the efficacy of acupuncture for GBS is warranted.
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How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.001 |
| Meta-epidemiology (narrow) | 0.001 | 0.000 |
| Meta-epidemiology (broad) | 0.001 | 0.001 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".