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Loss of DMP1 causes rickets and osteomalacia and identifies a role for osteocytes in mineral metabolism

2006· article· en· 1,198 citations· W2051959338 on OpenAlex· 10.1038/ng1905

Why is this work in the frame?

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

Canadian affiliationAn author listed a Canadian institution. This is the only route the usual frame has.

Machine scores (provisional)

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Opus teacher head0.006
GPT teacher head0.265
Teacher spread
0.259 · how far apart the two teachers sit on this one work
Validation status
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Abstract

No abstract. This is not a gap in this database — OpenAlex has none either. 23.3% of the frame is in this state, and the screen finds HALF as much metaresearch here, so the absence is a measured bias rather than a missing field.

The record

Venue
Nature Genetics
Topic
Parathyroid Disorders and Treatments
Field
Medicine
Canadian institutions
Shriners Hospitals for Children - CanadaMcGill UniversityChildren's Hospital of Eastern Ontario
Funders
National Institute of Dental and Craniofacial ResearchNational Institute of Arthritis and Musculoskeletal and Skin DiseasesNational Institute of Diabetes and Digestive and Kidney Diseases
Keywords
DMP1PHEXHypophosphatemic RicketsOsteocyteRicketsFibroblast growth factor 23OsteomalaciaHypophosphatemiaBiologyEndocrinologyBone remodelingInternal medicineOsteoblastOsteosclerosisOsteoclastGeneticsPathologyGeneMedicineCalciumVitamin D and neurologyParathyroid hormone
Has abstract in OpenAlex
no