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Record W2052535901 · doi:10.1186/1472-6882-12-s1-p179

P02.123. The anti-diabetic and cholesterol-lowering effects of common and cassia cinnamon (Cinnamomum verum and C. aromaticum): a randomized controlled trial

2012· article· en· W2052535901 on OpenAlexaff
Jean-Jacques Dugoua, Dan Perri, Dugald Seely, Jean‐Luc Ardilouze, Rowena Ridout, Katherine Bowers, Thomas R. Einarson, Gideon Koren

Bibliographic record

VenueBMC Complementary and Alternative Medicine · 2012
Typearticle
Languageen
FieldMedicine
TopicNatural Antidiabetic Agents Studies
Canadian institutionsCentre Hospitalier Universitaire de SherbrookeToronto Western HospitalCanadian College of Naturopathic MedicineMcMaster UniversityUniversity of Toronto
Fundersnot available
KeywordsMedicineCassiaTraditional medicineCinnamomumPhytotherapyRandomized controlled trialDiabetes mellitusAlternative medicineInternal medicineTraditional Chinese medicineEndocrinology

Abstract

fetched live from OpenAlex

Fifty (50) type 2 diabetic participants were randomized to receive either 140 mg of Cinnamonforce twice daily or placebo over 13 weeks. Physical and laboratory measurements were taken at baseline, 2 weeks, 4 weeks, 8 weeks and at the end of the trial, 13 weeks. There were no significant improvements in fasting glucose, insulin and lipid parameters between treatment and placebo groups. At endpoint, subjects in the treatment group were found to have a marginally non-significant higher fasting blood glucose level than subjects taking the placebo (p=0.085). There was a non-significant decrease in HA1c in the treatment group versus the placebo group (p=0.172). In secondary outcomes, significant differences in weight (p= 0.008), BMI (p= 0.001) and waist-to-hip ratio (p=0.020) were detected in the treatment versus placebo groups. The combination of common and cassia cinnamon do not impact fasting glucose, insulin and lipid measurements. Through power calculations, there may be an effect on HA1c, however, the sample size in this study was not sufficient to detect a trend, if any. Although secondary outcomes in this study, common and cassia cinnamon should be further investigated for weight loss.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.002
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Randomized trial · Consensus signal: Randomized trial
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.018
Threshold uncertainty score0.061

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.002
Meta-epidemiology (narrow)0.0010.001
Meta-epidemiology (broad)0.0030.002
Bibliometrics0.0000.001
Science and technology studies0.0000.001
Scholarly communication0.0010.001
Open science0.0010.000
Research integrity0.0030.002
Insufficient payload (model declined to judge)0.0180.002

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.023
GPT teacher head0.304
Teacher spread0.281 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designRandomized trial
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations7
Published2012
Admission routes1
Has abstractyes

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