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Osteoarthritis: New Insights

2002· letter· en· W2053702549 on OpenAlex

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

aboutThe title or abstract carries a Canadian signal from the geographic lexicon.
no affNo Canadian affiliation: this work is invisible to an affiliation-only frame.
No Canadian affiliation. An affiliation-only frame, the usual design, would never have seen this work. It is one of the works that make the case for inverting the frame.

Bibliographic record

VenueAnnals of Internal Medicine · 2002
Typeletter
Languageen
FieldMedicine
TopicMedicinal plant effects and applications
Canadian institutionsnot available
Fundersnot available
KeywordsViscosupplementationOsteoarthritisMedicineFood and drug administrationInternal medicinePhysical therapyAlternative medicinePharmacologyIntra articularPathology

Abstract

fetched live from OpenAlex

Letters1 January 2002Osteoarthritis: New InsightsDavid D. Waddell, MDDavid D. Waddell, MDLouisiana State University, Shreveport, LA 71103Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-136-1-200201010-00016 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail TO THE EDITOR:The authors of the review series on osteoarthritis (1) are to be commended for their effort to focus attention on advances in treatment and for their well-referenced, concise summary. Primary care providers need to become familiar with all options in order to offer comprehensive treatment programs. The omission of viscosupplementation, therefore, was surprising. The U.S. Food and Drug Administration approved hyaluronan-based viscosupplements in 1997 for the treatment of symptoms of knee osteoarthritis after failure of nonpharmacologic therapy and acetaminophen. Viscosupplements have been used clinically for osteoarthritis in Europe and Japan for over 10 years, and a high-molecular-weight ...References1. Felson DT, Lawrence RC, Hochberg MC, McAlindon T, Dieppe PA, Minor MA, et al . Osteoarthritis: new insights. Part 2: treatment approaches. Ann Intern Med. 2000;133:726-37. [PMID: 11074906] LinkGoogle Scholar2. Adams ME, Atkinson MH, Lussier AJ, Schulz JI, Siminovitch KA, Wade JP, et al . The role of viscosupplementation with hylan G-F 20 (Synvisc) in the treatment of osteoarthritis of the knee: a Canadian multicenter trial comparing hylan G-F 20 alone, hylan G-F 20 with non-steroidal anti-inflammatory drugs (NSAIDs) and NSAIDs alone. Osteoarthritis Cartilage. 1995;3:213-25. [PMID: 8689457] CrossrefMedlineGoogle Scholar3. Wobig M, Dickhut A, Maier R, Vetter G. Viscosupplementation with hylan G-F 20: a 26-week controlled trial of efficacy and safety in the osteoarthritic knee. Clin Ther. 1998;20:410-23. [PMID: 9663358] CrossrefMedlineGoogle Scholar4. Weiss C, Waddell D, Miller E. The availability of highly elastoviscous hylan for viscosupplementation can delay knee replacement in patients with advanced osteoarthritis. In: Kennedy JF, Phillips GO, Williams PA, Hascall VC, eds. Hyaluronan 2000. Cambridge: Woodhead; [In press]. Google Scholar5. Wobig M, Beks P, Dickhut A, Maier R, Vetter G. Open-label multicenter trial of the safety and efficacy of viscosupplementation with hylan G-F 20 (Synvisc) in primary osteoarthritis of the knee. J Clin Rheumatol. 1999;5 Suppl 6 S24-S31. Google Scholar Author, Article, and Disclosure InformationAuthors: David D. Waddell, MDAffiliations: Louisiana State University, Shreveport, LA 71103 PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetailsSee AlsoOsteoarthritis: New Insights. Part 2: Treatment Approaches Conference Chair: David T. Felson , Conference Organizer: Reva C. Lawrence , Discussants: Marc C. Hochberg , Timothy McAlindon , Paul A. Dieppe , Marian A. Minor , Steven N. Blair , Brian M. Berman , James F. Fries , Morris Weinberger , Kate R. Lorig , Joshua J. Jacobs , and Victor Goldberg Osteoarthritis: New Insights Paul J. Rosch Osteoarthritis: New Insights Robert H. Palmer Osteoarthritis: New Insights David T. Felson and Timothy McAlindon Osteoarthritis: New Insights Thomas E. Lindow Metrics 1 January 2002Volume 136, Issue 1Page: 86KeywordsArthroscopyClinical trialsDrugsFood and Drug AdministrationKneesNSAIDsOrthopedicsOsteoarthritis ePublished: 1 January 2002 Issue Published: 1 January 2002 Copyright & PermissionsCopyright © 2002 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow), Insufficient payload (model declined to judge)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: Not applicable
GenreCandidate signal: Commentary · Consensus signal: Commentary
Teacher disagreement score0.019
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0010.002
Insufficient payload (model declined to judge)0.0020.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.061
GPT teacher head0.329
Teacher spread0.268 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it