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Incomplete Revascularization After Coronary Artery Bypass Graft Operations Is Independently Associated With Worse Long-Term Survival

2014· article· en· W2055073435 on OpenAlexaffabout
Valentin Mocanu, Karen J. Buth, Ryan Kelly, Jean‐François Légaré

Bibliographic record

VenueThe Annals of Thoracic Surgery · 2014
Typearticle
Languageen
FieldMedicine
TopicCardiac and Coronary Surgery Techniques
Canadian institutionsDalhousie University
Fundersnot available
KeywordsMedicineHazard ratioRevascularizationConfidence intervalProportional hazards modelCardiologyDerivationInternal medicineSurgeryArteryMyocardial infarction

Abstract

fetched live from OpenAlex

BACKGROUND: Complete revascularization (CR) has been suggested to provide benefits to both early and long-term outcomes, but the magnitude of the benefit and frequency of incomplete revascularization (IR) after coronary artery bypass graft operations is rarely explored and is the subject of the present study. METHODS: All patients who underwent isolated bypass operations (March 1995 to September 2007) at the Queen Elizabeth II Health Sciences Center (Halifax, NS, Canada) were identified. Revascularization was considered complete if each significantly diseased territory received at least 1 graft. Clinical characteristics of the CR and IR groups were examined to determine barriers of CR. A nonparsimonious Cox proportion model and survival curves were constructed to examine the association of CR and death after adjusting for clinically relevant covariates. RESULTS: A total of 8,570 patients underwent isolated nonredo bypass operations. IR, based on our strict definition, occurred in 19% of the patients. The territories most commonly affected were the right coronary and circumflex coronary territories. After adjustment for relevant clinical differences, IR was a significant independent predictor of long-term mortality (hazard ratio, 1.2; 95% confidence interval, 1.1 to 1.3). IR was also a significant independent predictor of hospital readmission for cardiac reasons after discharge (hazard ratio, 1.2; 95% confidence interval, 1.0 to 1.3). CONCLUSIONS: Despite advances in surgical revascularization, IR can occur in up to 19% of patients. IR significantly affects long-term death and readmission to hospital for cardiac reasons, and avoiding IR should therefore be a priority for surgeons during preoperative planning.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.004
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.003
Threshold uncertainty score0.009

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.004
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0010.000
Open science0.0000.001
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0030.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.055
GPT teacher head0.330
Teacher spread0.275 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations18
Published2014
Admission routes2
Has abstractyes

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