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Filling in the gaps: EST surveys of under‐represented chromalveolates

2005· article· en· W2059382120 on OpenAlexaff
Ross F. Waller, Nicola J. Patron, Patrick J. Keeling

Bibliographic record

VenueJournal of Eukaryotic Microbiology · 2005
Typearticle
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicProtist diversity and phylogeny
Canadian institutionsUniversity of British Columbia
Fundersnot available
KeywordsBiologyPlastidMonophylyEndosymbiosisEvolutionary biologyPhylogenomicsHaptophyteCladeMost recent common ancestorProtistGenomePhylogeneticsGeneticsGeneEcologyChloroplast

Abstract

fetched live from OpenAlex

The “chromalveolate hypothesis” posits the monophyly of alveolates (apicomplexans, dinoflagellates and ciliates), heterokonts, haptophytes and cryptomonads. One implication of the monophyly of chromalveolates is that the plastids in this group could share a common ancestor—derived from a single endosymbiosis. Members of all chromalveolate groups, with the exception of ciliates, possess a secondary plastid originating from a rhodophytic symbiont (although the rhodophytic origin of the apicomplexan plastid remains contentious). A single origin of this chromalveolate plastid represents the most parsimonious hypothesis for plastid acquisition. Growing support for the “chromalveolate hypothesis” has relied on a relatively small number of molecular studies to date, and a more thorough examination of this alliance has been undermined by a paucity of broad molecular data from several of its members, despite complete genome sequences from apicomplexans and ciliates. To address this deficit we have undertaken EST (Expressed Sequence Tag) surveys of several taxa, representing dinoflagellates, haptophytes and cryptomonads. Using EST data we are undertaking broad molecular comparisons of these groups through molecular phylogenies, analyses of common biochemical pathways, and studies of organelle evolution. This genome‐based approach provides a more complete view of the major chromalveolate groups, and a chance to more thoroughly test the chromalveolate hypothesis.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.002
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.001
Threshold uncertainty score0.007

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.002
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0010.002
Science and technology studies0.0000.000
Scholarly communication0.0010.001
Open science0.0000.001
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0010.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.013
GPT teacher head0.242
Teacher spread0.229 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2005
Admission routes1
Has abstractyes

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