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Record W2060751984 · doi:10.1051/ocl/2013057

Les effets neurocognitifs de la vitamine D chez la personne âgée

2014· article· fr· W2060751984 on OpenAlex

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

affAt least one author lists a Canadian institution in the pinned OpenAlex snapshot.

Bibliographic record

VenueOCL · 2014
Typearticle
Languagefr
FieldMedicine
TopicVitamin D Research Studies
Canadian institutionsWestern University
Fundersnot available
KeywordsPhilosophy

Abstract

fetched live from OpenAlex

Une alimentation saine, en particulier la consommation rgulire d'aliments riches en vitamine D, est un facteur protecteur contre la survenue de pathologie dmentielle chez la personne ge. Outre ses proprits traditionnellement reconnues de rgulation du mtabolisme phosphocalcique, la vitamine D est une hormone neurostrode indispensable au fonctionnement neurophysiologique (rgulation de neurotransmetteurs et de neurotrophines) avec, en plus, une action neuroprotectrice anti-inflammatoire et anti-oxydante. Au contraire son insuffisance, extrmement prvalente chez la personne ge, pourrait engendrer des dysfonctionnements du systme nerveux central, expliquant en partie les troubles cognitifs rencontrs dans cette population. L'pidmiologie est cohrente avec cette notion et rapporte une association entre hypovitaminose D et trouble cognitif, que ce soit en population ge gnrale ou chez le malade Alzheimer. Les essais d'intervention confirment la relation de causalit et quantifient l'efficacit cognitive de la supplmentation vitaminique D chez la personne ge, ce qui suscite des perspectives en matire de prvention primosecondaire des troubles cognitifs chez la personne ge par un apport exogne de vitamine D. En particulier, tandis que les traitements anti-dmence symptomatiques actuellement disponibles ne font que ralentir transitoirement le dclin cognitif, les futures possibilits de traitement pourraient reposer sur des combinaisons mdicamenteuses luttant contre plusieurs mcanismes neurodgnratifs la fois. ce titre, la vitamine D amliore l'efficacit de la mmantine en termes de protection neuronale et de prvention du dclin cognitif au cours de la maladie d'Alzheimer.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.002
metaresearch head score (Gemma)0.006
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow), Insufficient payload (model declined to judge)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Other design · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.659
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0020.006
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0000.000
Science and technology studies0.0000.001
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0010.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.015
GPT teacher head0.320
Teacher spread0.305 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it