FP41 Cardiovascular Haemodynamics during Pain in Healthy Persons and in Persons with Ischaemic Heart Disease
Bibliographic record
Abstract
Purpose: Haemodynamic function during pain is not well understood. The aim of this review was to evaluate the literature of cardiovascular function during pain, specifically the haemodynamics underlying pain in healthy adults and in adults with ischaemic heart disease (IHD). Inclusion criteria: Studies were included that measured haemodynamics during pain in healthy adults and in adults with IHD. Pain was defined as the subjective response to noxious stimuli, such as the cold pressor test or induced coronary artery occlusion. Haemodynamic response was defined as changes in heart rate (HR), blood pressure (BP), cardiac output (CO), stroke volume (SV), and/or systemic vascular resistance (SVR). Methods: Electronic searches were conducted of The Cochrane Library, MEDLINE and CINAHL databases. The search was limited to the past twenty years (1988–2008) and studies in English using the terms haemo-dynamic parameters, BP, HR, SVR, ischaemic cascade, neurochemical cascade, pain, BP and pain, acute myocardial infarction, cardiac nociception, impedance cardiography, thoracic impedance, and ambulatory impedance cardiography. Published studies, abstracts, relevant journals, and reference lists of retrieved articles were reviewed. Dissertations and conference proceedings were not reviewed.
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.002 | 0.010 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.002 | 0.001 |
| Bibliometrics | 0.003 | 0.004 |
| Science and technology studies | 0.000 | 0.001 |
| Scholarly communication | 0.002 | 0.001 |
| Open science | 0.001 | 0.000 |
| Research integrity | 0.001 | 0.000 |
| Insufficient payload (model declined to judge) | 0.007 | 0.001 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".