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Record W2062084207 · doi:10.1080/09553000801953300

Altered blood chemistry and hippocampal histomorphology in adult rats following prenatal exposure to physiologically-patterned, weak (50–500 nanoTesla range) magnetic fields

2008· article· en· W2062084207 on OpenAlexaff
Linda S. St-Pierre, A. Mazzuchin, Michael A. Persinger

Bibliographic record

VenueInternational Journal of Radiation Biology · 2008
Typearticle
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicElectromagnetic Fields and Biological Effects
Canadian institutionsLaurentian UniversityCambrian College
Fundersnot available
KeywordsHippocampal formationHippocampusEndocrinologyInternal medicinePrenatal developmentPrenatal exposureAdult maleChemistryFetusNuclear magnetic resonanceBiologyMedicinePregnancyGestationGenetics

Abstract

fetched live from OpenAlex

PURPOSE: To discern changes in blood chemistry, cerebral sizes, and hippocampal cytomorphology in adult male and female albino Wistar rats that had been exposed during their entire prenatal development to one of two patterns of magnetic fields and one of four intensities: Very low 5 - 20 nT; low 30 - 50 nT; medium 90 - 580 nT; and high 590 nT to 1.2 microT. MATERIALS AND METHODS: A total of 48 pregnant females were exposed to either a repetitive frequency-modulated magnetic field or to a complex sequence of 50, 200-msec physiologically-patterned fields. As adults blood, cerebral, and histomorphological data were obtained from the 137 rats that had been exposed to one of these eight conditions. RESULTS: Compared to other groups, adult rats that had been exposed prenatally to the physiologically-patterned magnetic fields at the low (30 - 50 nT) and medium (90 - 580 nT) intensities exhibited peak elevations of aminotransaminase, glucose, and uric acid. Numbers of cytometric anomalies were also significantly elevated within regions of the hippocampus known for neuronal neogenesis in adults. CONCLUSIONS: The results suggest that a common factor in cellular adhesion or plasticity might be permanently altered by prenatal exposure to a narrow intensity of a series of physiologically-patterned magnetic fields.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.400
Threshold uncertainty score0.588

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.005
GPT teacher head0.231
Teacher spread0.225 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations18
Published2008
Admission routes1
Has abstractyes

Explore more

Same venueInternational Journal of Radiation BiologySame topicElectromagnetic Fields and Biological EffectsFrench-language works237,207