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Record W2062199028 · doi:10.1021/ac900711b

Overcoming Field Imperfections of Quadrupole Mass Filters with Mass Analysis in Islands of Stability

2009· article· en· W2062199028 on OpenAlexaff
XianZhen Zhao, Zilan Xiao, D. J. Douglas

Bibliographic record

VenueAnalytical Chemistry · 2009
Typearticle
Languageen
FieldChemistry
TopicMass Spectrometry Techniques and Applications
Canadian institutionsUniversity of British Columbia
Fundersnot available
KeywordsQuadrupoleChemistryRodQuadrupole mass analyzerField (mathematics)Stability (learning theory)HarmonicsComputational physicsAtomic physicsAnalytical Chemistry (journal)Mass spectrometryMolecular physicsPhysicsChromatographyVoltage

Abstract

fetched live from OpenAlex

We have constructed, and tested as mass filters, linear quadrupoles with added hexapole fields of 4%, 8%, and 12%, with and without added octopole fields. A hexapole field can be added to the field of a linear quadrupole by rotating the two y rods toward an x rod. This also adds an octopole field which can be removed by making the x rods greater in diameter than the y rods. In comparison to conventional quadrupole mass filters these rod sets have severely distorted quadrupole fields, with a mix of both even and odd higher spatial harmonics. They allow evaluating the performance of rod sets with strong geometric and field distortions as mass filters. Conventional mass analysis at the tip of the stability diagram has been compared to mass analysis using islands of stability. The stability islands are produced by applying an auxiliary quadrupole excitation field to the quadrupole. We show that with normal mass analysis at the tip of the stability diagram, the transmission, resolution, and peak shapes are relatively poor in comparison to a conventional rod set. However, the use of islands of stability dramatically improves the resolution and peak shape, and in some cases ion transmission, suggesting that mass analysis with islands of stability may provide a method to overcome a wide range of field imperfections in linear quadrupole mass filters.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.003
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.001
Threshold uncertainty score0.007

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.003
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.001
Scholarly communication0.0010.001
Open science0.0010.001
Research integrity0.0010.000
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.009
GPT teacher head0.260
Teacher spread0.251 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations17
Published2009
Admission routes1
Has abstractyes

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