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Malignant hyperpyrexia and the laryngeal mask airway

2001· letter· en· W2062438607 on OpenAlexfundno aff
Christopher Danbury, K. Torlot

Bibliographic record

VenueAnaesthesia · 2001
Typeletter
Languageen
FieldMedicine
TopicAirway Management and Intubation Techniques
Canadian institutionsnot available
FundersMcGill University
KeywordsMedicineLaryngeal mask airwayAirwayAnesthesiaMascaraPropofolLarynxLaryngeal MasksSiliconeSurgery

Abstract

fetched live from OpenAlex

Recently, we had occasion to anaesthetise a patient, who was susceptible to malignant hyperpyrexia, for the incision and drainage of a peri-anal abscess. She was a fit and healthy 19-year-old with no significant past medical history. She was well starved and we proposed to induce her with fentanyl 1–2 µg.kg−l, propofol 2 mg.kg−l and maintain anaesthesia with a propofol infusion. We had decided to let her breathe spontaneously on a laryngeal mask. However, on consideration, it was unclear whether the techniques used for cleaning laryngeal mask airways were sufficient to ensure that no volatile agent remained adsorbed onto the surface of a pre-used laryngeal mask. A discussion with Intavent followed and the company was also unsure as to whether normal cleaning would completely remove any traces of volatile agents from a laryngeal mask airway. A review of the literature shows that flushing silicone tubing with oxygen for over 1 h does not remove volatile agents and that normal decontamination procedures of rubber and silicone products reduce volatile anaesthetics to a variable extent [1]. Further review (Medline) has been unable to discover any cases of malignant hyperpyrexia triggered by the re-use of a laryngeal mask. We felt that to use a pre-used laryngeal mask would expose our patient to an unquantifiable, but unnecessary risk. Therefore, we used a disposable laryngeal mask airway in addition to the usual fresh breathing system and a vapour-free machine. The patient was anaesthetised without any ill effects.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesInsufficient payload (model declined to judge)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: Not applicable
GenreCandidate signal: Commentary · Consensus signal: Commentary
Teacher disagreement score0.124
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.014
GPT teacher head0.237
Teacher spread0.223 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designNot applicable
Domainnot available
GenreCommentary

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2001
Admission routes1
Has abstractyes

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