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Record W2064223697 · doi:10.1021/om060914f

Extremely Stable Thorium(IV) Dialkyl Complexes Supported by Rigid Tridentate 4,5-Bis(anilido)xanthene and 2,6-Bis(anilidomethyl)pyridine Ligands

2007· article· en· W2064223697 on OpenAlexaff
Carlos Cruz, David J. H. Emslie, L.E. Harrington, James F. Britten, Craig M. Robertson

Bibliographic record

VenueOrganometallics · 2007
Typearticle
Languageen
FieldChemistry
TopicOrganometallic Complex Synthesis and Catalysis
Canadian institutionsMcMaster University
Fundersnot available
KeywordsChemistryAgostic interactionDeprotonationMedicinal chemistryLigand (biochemistry)PyridinePentagonal bipyramidal molecular geometryTolueneCrystal structureCrystallographyOrganic chemistryIon

Abstract

fetched live from OpenAlex

A new NON-donor ligand, 4,5-bis(2,6-diisopropylanilino)-2,7-di- tert -butyl-9,9-dimethylxanthene (H 2 [XA 2 ], 1 ), was prepared by palladium-catalyzed coupling of 2,6-diisopropylaniline with the appropriate dibromoxanthene precursor. Stable K 2 (dme) 2 [XA 2 ] ( 2 ) and Na 2 [XA 2 ] ( 3 ) salts were accessible by deprotonation of H 2 [XA 2 ] with KH in dme or NaH in toluene. The thermally unstable lithium salt of McConville's 2,6-bis(2,6-diisopropylanilidomethyl)pyridine ligand (Li 2 [BDPP], 4 ) was isolated by deprotonation with n BuLi or LiCH 2 SiMe 3 in hexanes at low temperature. Reaction of [ThCl 4 (dme) 2 ] with Li 2 [BDPP] or M 2 (dme) n [XA 2 ] resulted in the formation of pentagonal bipyramidal [LThCl 2 (dme)] complexes (L = BDPP, 5; XA 2, 6 ). Subsequent reaction of 5 or 6 with LiCH 2 SiMe 3 gave base- and salt-free dialkyl complexes, [LTh(CH 2 SiMe 3 ) 2 ] (L = BDPP, 7; XA 2, 8 ), which are stable for days in solution at 90 and 70 °C, respectively. Complexes 5, 7, and 8 were also accessible by initial combination of 2 or 4 equiv of LiCH 2 SiMe 3 with [ThCl 4 (dme) 2 ], followed by addition of H 2 L. These reactions likely proceed by alkane elimination, but dialkyl or tetraalkyl thorium intermediates were not identified. The X-ray crystal structure of 8 suggests the presence of α-agostic C−H−Th interactions for both alkyl groups. In solution, 7 and 8 exhibit temperature-dependent 1 J C,H coupling constants for Th CH 2, demonstrating the presence of α-agostic interactions which become increasingly favored at lower temperature. Reaction of 5 with Li 2 [BDPP] at 0 °C or 7 with H 2 [BDPP] at 100 °C resulted in the formation of extremely sterically encumbered [Th(BDPP) 2 ] ( 9 ), which adopts a highly distorted six-coordinate geometry with the four anilido groups arranged in an approximate tetrahedron around thorium. Bis-ligand complexes were not accessible with the XA 2 platform, presumably due to increased ligand rigidity.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.001
Threshold uncertainty score0.005

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0010.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0010.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.013
GPT teacher head0.237
Teacher spread0.223 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations81
Published2007
Admission routes1
Has abstractyes

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