MétaCan
Menu
Back to cohort

Evolving Insights: Symbiosis Islands and Horizontal Gene Transfer

2002· letter· en· W2067702417 on OpenAlexaff
Turlough M. Finan

Bibliographic record

VenueJournal of Bacteriology · 2002
Typeletter
Languageen
FieldAgricultural and Biological Sciences
TopicLegume Nitrogen Fixing Symbiosis
Canadian institutionsMcMaster University
Fundersnot available
KeywordsBiologyHorizontal gene transferPathogenicity islandGenomeSymbiosisGenomic islandGeneticsMesorhizobiumGeneEvolutionary biologyGenome evolutionPlasmidRhizobiaComparative genomicsGenomicsBacteria

Abstract

fetched live from OpenAlex

A common theme emerging from microbial genome studies is that the genes required for pathogenic or symbiotic interactions with eukaryotic hosts are often part of the accessory gene pool of the microbe, acquired by horizontal transfer (5). They may be clustered on plasmids or on the chromosome as genomic islands. Within a particular environment, such islands provide a selective advantage to organisms that carry them, leading to the term “fitness islands” (7), with the pathogenicity islands (PAIs) that endow many bacterial pathogens with their virulence constituting a particular subset (1). In many cases it appears that the transfer machinery of genomic islands has been lost through reductive evolution following their acquisition, anchoring the islands in the host chromosome (2). However, a particularly striking example of a genomic island that has retained its transmissibility is the Mesorhizobium loti strain R7A symbiosis island. The research that led to the characterization of this island represents an engaging and attractive “case history,” in which initial findings from a field experiment have logically progressed to the report by Sullivan et al. (10) in this issue of the sequence and annotation of the entire 502-kb island. This work impacts on diverse areas of microbiology, including the rhizobium-legume symbiosis, microbial ecology, and microbial evolution.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesInsufficient payload (model declined to judge)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.757
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0010.002
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.014
GPT teacher head0.191
Teacher spread0.177 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designNot applicable
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations68
Published2002
Admission routes1
Has abstractyes

Explore more

Same venueJournal of BacteriologySame topicLegume Nitrogen Fixing SymbiosisFrench-language works237,207