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P5-S6.23 Barriers to accessing hepatitis C treatment for individuals who have experience with injection drug use

2011· article· en· W2067792640 on OpenAlexaffabout
Caitlin Sinclair, Susan Kirkland, Mark Asbridge, Fiona Martin

Bibliographic record

VenueSexually Transmitted Infections · 2011
Typearticle
Languageen
FieldMedicine
TopicHepatitis C virus research
Canadian institutionsDalhousie University
Fundersnot available
KeywordsMedicineHepatitis CMethadoneHepatitisHepatitis BMethadone maintenanceHuman immunodeficiency virus (HIV)AddictionFamily medicineInternal medicinePsychiatry

Abstract

fetched live from OpenAlex

In Canada, approximately 10 000 people are living with both hepatitis C and HIV; 20% of individuals living with HIV are co-infected with hepatitis C. Many individuals who inject drugs are at a higher risk for contracting both hepatitis C and HIV because they engage in high risk activities that increase their chances of being in contact with infected blood Individuals living with hepatitis C are at risk of contracting HIV. Being co-infected with both diseases complicates both hepatitis C and HIV; it is therefore critical to provide treatment for hepatitis C. Although those living with hepatitis C often report high interested in treatment, uptake remains low. The purpose of this research project is to identify the factors which influence decisions around hepatitis C treatment. A mixed methods approach was used; 60 individuals participated in a cross sectional questionnaire, while 6 engaged in in-depth interviews. All participants were currently accessing methadone maintenance treatment for opioid addiction and had experience with injection drug use. The questionnaires explored characteristics, knowledge, attitude and willingness to access hepatitis C treatment. Interviews delved deeper into the issues uncovered in the questionnaires and explored life experiences and their influence around treatment decisions. Results indicated that 70% of participants were interested in starting hepatitis C treatment within the next 6 months, while 30% were undecided or uninterested. Analysis of the questionnaire results have suggested that it may not be factual knowledge which influences individuals' decisions around treatment, but life conditions (ie, housing, employment) and experiences. The interviews supported this finding though a thematic analysis. The results of this study suggest that efforts to increase interest in treatment should focus on improving life conditions that support accessing treatment (eg, providing supportive housing). Future studies would include a larger sample size and a more refined questionnaire.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.113
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0010.001
Science and technology studies0.0010.000
Scholarly communication0.0000.001
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.060
GPT teacher head0.340
Teacher spread0.281 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2011
Admission routes2
Has abstractyes

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