A tale of two ventricles: ventricular-ventricular interactions and LV dysfunction after surgical repair of Tetralogy of Fallot
Bibliographic record
Abstract
Tetralogy of Fallot (TOF) is the most common cyanotic congenital heart defect with good long-term survival after surgical correction.1 Nonetheless, patients suffer from significant morbidity and mortality including exercise intolerance, arrhythmias, and sudden death, presenting an important healthcare burden.2 To date, most clinical and research emphasis in TOF has been placed on right ventricular (RV) pathology. Indeed, progressive RV dilatation and dysfunction are common and are well-established risk factors for adverse clinical outcomes.3,4 In contrast, relatively little attention has been paid to left ventricular (LV) dysfunction and to adverse ventricular–ventricular interactions in this population. However, recent studies show that LV dysfunction is not only common in adults after TOF repair, but is linked to adverse clinical outcomes.5–7 The mechanisms driving LV dysfunction in this population appear to be related, at least in part, to RV dysfunction.8 RV and LV ejection fraction (EF) are closely related after TOF repair, and myocardial deformation studies demonstrate impairment in multiple components of both RV …
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How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.002 | 0.001 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.002 | 0.004 |
| Bibliometrics | 0.001 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.001 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".