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Record W2071634752 · doi:10.1159/000112457

The Metabolic Syndrome: Definitions, Prevalence and Management

2008· review· en· W2071634752 on OpenAlexaff
J Levesque, Benoı̂t Lamarche

Bibliographic record

VenueLifestyle Genomics · 2008
Typereview
Languageen
FieldMedicine
TopicDiabetes, Cardiovascular Risks, and Lipoproteins
Canadian institutionsUniversité Laval
Fundersnot available
KeywordsMetabolic syndromeMedicineDyslipidemiaAbdominal obesityDiseaseFramingham Risk ScoreObesityFramingham Heart StudyDiabetes mellitusType 2 diabetesIntensive care medicineInternal medicineEndocrinology

Abstract

fetched live from OpenAlex

The metabolic syndrome (MetS) refers to the clustering of various metabolic risk factors that include abdominal obesity, dyslipidemia, hypertension, and hyperglycemia. It is now well known that it is associated with an increased risk of cardiovascular disease (CVD) and of type 2 diabetes. The increasing prevalence of the MetS, associated with the substantial progression of obesity and diabetes, is therefore an important public health concern. Over the years, several definitions for the MetS have been proposed by major scientific associations. Those definitions differ somewhat in their criteria and threshold values but generally all agree on the essential components of the syndrome. The proposed definitions are intended to help identify individuals at increased long-term risk of CVD, who could benefit from early prevention. The diagnosis of the MetS should be used concurrently with standard predicting algorithms, such as the Framingham Risk Score and the Diabetes Predicting Model, which better predict short-term risks. The management of the MetS should emphasize therapeutic lifestyle modifications--weight loss, increased physical activity, healthy diet--as the first-line therapy. If the short-term risk of CVD or diabetes is high, specific risk factors should be monitored more closely according to established guidelines and drug therapy may be appropriate.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: none
GenreCandidate signal: Review · Consensus signal: Review
Teacher disagreement score0.986
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0020.001
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.035
GPT teacher head0.269
Teacher spread0.234 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designNot applicable
Domainnot available
GenreReview

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations66
Published2008
Admission routes1
Has abstractyes

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