Biologically active compounds from European mistletoe (<i>Viscum album</i>L.)<sup>1</sup>
Bibliographic record
Abstract
European mistletoe (Viscum album L.) is a commonly occurring semiparasite of trees. The extracts from European mistletoe have been shown to possess immunostimulatory and cytotoxic activity on tumor cells, and are used in Europe in adjuvant cancer therapy. Recently, a number of studies performed have been leading to the identification and characterization of bioactive compounds. Apoptosis-inducing and ribosome-inactivating lectins as well as cytotoxic thionins (viscotoxins) are the main groups of compounds participating in biological activity of V. album. These compounds were isolated and studied in vitro and in vivo for their biological activity and mechanism of action. A comparison of the results to those using whole extracts indicated that lectins and viscotoxins are not the only bioactive compounds present in the mistletoe and among them, high heterogeneity is observed in both structure and activity. In this paper, we review the current state of the art in mistletoe studies, emphasizing its potential application as a drug, its standardization, and taxonomic problems. The nontherapeutic applications and suspected physiological functions of the compounds in question are also discussed briefly.
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.001 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".