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Record W2073080006 · doi:10.1118/1.4740191

Sci—Fri AM: Imaging — 05: Cone‐beam computed tomography for breast biopsy analysis: Simulations

2012· article· en· W2073080006 on OpenAlexaff
Curtis Laamanen, R. J. LeClair

Bibliographic record

VenueMedical Physics · 2012
Typearticle
Languageen
FieldMedicine
TopicDigital Radiography and Breast Imaging
Canadian institutionsLaurentian University
Fundersnot available
KeywordsCone beam computed tomographyImaging phantomComputed radiographyNuclear medicineMaterials scienceOpticsMedical imagingMagnificationX-rayCylinderContrast (vision)Detective quantum efficiencyBiopsyPhysicsMedicineComputed tomographyRadiologyImage qualityGeometryMathematicsComputer scienceArtificial intelligence

Abstract

fetched live from OpenAlex

PURPOSE: To determine the feasibility and potential utility of cone beam CT on breast biopsies. METHODS: CBCT simulations were done with a setup which emulates an MX-20 digital specimen radiography system (Faxitron X-Ray Corporation, Chicago, IL), albeit a DQE = 1 was assumed. The phantom consisted of a 5mm diameter cylinder with a length of 5mm, made up of a homogeneous 50:50 mixture of fibrous and fatty tissue. Small cancerous spheres (lesions) with diameters ranging from 5 to 500 μm were embedded. Projections were acquired at magnification 5 using 26 kV-0.3 mA-3.8 sec beams. Images were reconstructed using a varied number of projections (50, 100, 150, 300). Values of contrast and SNR were calculated between the lesions and nearby regions. Noise was estimated by generating 10 images for each task. Scatter was found to be negligible. RESULTS: The 50 μm spheres were only visible when at least 150 projections were used, but the 100 μm ones were visible regardless of the number. SNR increased with the number of projections, whereas contrast was insensitive. For ≥100 μm spheres contrast ranged from 0.26 on the outer radial edge to 0.28 nearer the center. The SNRs for 100 μm spheres were above 5 for reconstructions composed of ≥100 projections. Cancerous lesions within a fibrous biopsy may be detectable. CONCLUSIONS: The findings from this simulation study suggest that CBCT for breast biopsy characterization via the MX-20 system could be of potential use to see structures on the order of 100 μm.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: none
Teacher disagreement score0.631
Threshold uncertainty score0.861

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0000.002
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.014
GPT teacher head0.281
Teacher spread0.267 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

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Citations0
Published2012
Admission routes1
Has abstractyes

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