P3.016 Prevalence and Correlates of Rectal-Only Chlamydia Infection at Two Canadian STI Clinics
Bibliographic record
Abstract
<h3>Background</h3> In July 2012, two Alberta Sexually Transmitted Infection (STI) Clinics changed their testing platform for rectal chlamydia (CT) from cell culture to nucleic acid amplification testing (NAAT). A significant increase in the proportion of rectal-only CT cases occurred after the introduction of NAAT (1.9%; n = 25 pre-NAAT vs. 20.1%; n = 245 post-NAAT, <i>P</i> < 0.001). We sought to examine the characteristics of rectal-only CT cases. <h3>Methods</h3> All CT cases seen at two Alberta STI clinics between July 20 and December 31, 2012 were extracted from the provincial STI database. Variables included were demographics, clinical history, reasons for visit and site of infection. Cases positive from the rectum alone were compared with cases positive from urethra, cervix, vault and urine alone or in multiple sites including the rectum. CT testing was conducted with Genprobe Aptima by the Provincial Laboratory for Public Health. Univariate analysis was completed using Chi-square or Fisher’s exact test and Mann-Whitney for continuous variables. Bivariate logistic regression, adjusted for gender, was completed using significant (<i>P</i> > 0.05)at the univariate level. <h3>Results</h3> Twenty percent of all CT cases (n = 245) were diagnosed in the rectum only; females were more likely to be diagnosed with rectal-only CT (24.6%) than males (16.6%; <i>P</i> = 0.001). No cases of rectal-only CT were found among heterosexual men; therefore regression models were completed for women and men who have sex with men (MSM). Factors associated with rectal-only CT for women included older age (AOR = 1.05, 95% CI: 1.02, 1.08), being tested at Clinic A (AOR = 3.0, 95% CI: 1.8, 5.1), and being named as a contact to an STI (AOR = 0.3, 95% CI: 0.1, 0.9). For MSM, being asymptomatic (AOR = 2.2, 95% CI: 1.2, 4.1) remained significant. <h3>Conclusions</h3> After the switch to NAAT testing for rectal CT, additional cases of CT were found among women and MSM. Differences between clinics are likely attributable to different screening practises for women.
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How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.001 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.001 | 0.001 |
| Science and technology studies | 0.001 | 0.001 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.001 |
| Insufficient payload (model declined to judge) | 0.003 | 0.001 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; both teacher heads agree on what is shown here.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".