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Record W2074518132 · doi:10.1086/587747

An Elderly Woman with a Diffuse Annular Eruption

2008· article· en· W2074518132 on OpenAlexaff
Donald C. Vinh, Nolan Finlayson, John M. Toole, Sate Hamza, John M. Embil

Bibliographic record

VenueClinical Infectious Diseases · 2008
Typearticle
Languageen
FieldMedicine
TopicLeprosy Research and Treatment
Canadian institutionsUniversity of ManitobaSeven Oaks General Hospital
Fundersnot available
KeywordsMedicineDermatology

Abstract

fetched live from OpenAlex

Diagnosis: borderline leprosy. The diagnosis of leprosy was suspected on the basis of the presence of erythematous annular skin lesions associated with hypoesthesia in a woman originating from the Philippines, where Mycobacterium leprae infection is endemic. It was confirmed by punch biopsy of an active skin lesion on the forehead (figure 1), which revealed granulomatous dermatitis, neural inflammation, and easily identifiable acid-fast bacilli (AFB) (figure 2). Bacterial and fungal cultures were sterile. Leprosy, also known as Hansen disease, is a chronic granulomatous infection of the skin and peripheral nerves by the noncultivable obligate intracellular pathogen M. leprae. Globally, the majority of cases occur in India, South America, and Southeast Asia [1]. In North America, it is usually seen among immigrants from regions where the disease is endemic and typically occurs within the first year after arrival [2]. Unfamiliarity with this disease may lead to delayed diagnosis, as in this case. Humans are the major reservoirs of M. leprae, although infection can occur in other animals (e.g., the 9-banded armadillo and monkeys) [3]. The proposed major route of human transmission is by aerosolized nasal droplets. Direct skin contact plays little, if any, role [1].

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.007
Threshold uncertainty score0.425

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.047
GPT teacher head0.388
Teacher spread0.341 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2008
Admission routes1
Has abstractyes

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