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A Randomized Trial of Ustekinumab, a Human Interleukin-12/23 Monoclonal Antibody, in Patients With Moderate-to-Severe Crohn's Disease

2008· article· en· 746 citations· W2075090387 on OpenAlex· 10.1053/j.gastro.2008.07.014

Why is this work in the frame?

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

Canadian affiliationAn author listed a Canadian institution. This is the only route the usual frame has.
Canadian funderA Canadian agency funded it. The work may carry no Canadian affiliation at all.

Machine scores (provisional)

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Opus teacher head0.007
GPT teacher head0.234
Teacher spread
0.227 · how far apart the two teachers sit on this one work
Validation status
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Abstract

No abstract. This is not a gap in this database — OpenAlex has none either. 23.3% of the frame is in this state, and the screen finds HALF as much metaresearch here, so the absence is a measured bias rather than a missing field.

The record

Venue
Gastroenterology
Topic
Inflammatory Bowel Disease
Field
Biochemistry, Genetics and Molecular Biology
Canadian institutions
University of AlbertaLondon Health Sciences Centre
Funders
National Center for Research ResourcesMedical Center, University of PittsburghVanderbilt University Medical CenterMcMaster UniversityUniversity of PittsburghCleveland Clinic FoundationKaiser PermanenteUniversity of Wisconsin-MadisonCleveland ClinicVanderbilt University
Keywords
UstekinumabCrohn's diseaseMedicineMonoclonal antibodyRandomized controlled trialMonoclonalInternal medicineGastroenterologyDiseaseInterleukin 23ImmunologyAntibodyInterleukinCytokineInfliximab
Has abstract in OpenAlex
no