Indices of Leukocyte Infiltration and Muscle Recovery After Eccentric Contraction-Induced Injury in Young and Adult Male Mice
Bibliographic record
Abstract
The movement of leukocytes (e.g., neutrophils and macrophages) into skeletal muscle is a critical response after a sports-related injury. Age could influence this response. The major objectives of the study were to determine whether there is a relationship between age and the degree of (1) leukocyte response and (2) muscle recovery. The left plantarflexor muscles of 42 young and adult male mice underwent eccentric contractions, which can cause injury. After 1 or 5 days, leukocyte infiltration and muscle recovery were assessed in the soleus or medial gastrocnemius muscles. No relationship between age and leukocyte infiltration was found (P = .36). Neutrophils, but not macrophages, were detected at 1-day recovery. A significant relationship between age and muscle recovery was detected (P = .0498), suggesting that muscle recovery may be decreased with increased age.
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How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".