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Effectiveness of catheter hub sanitation prior to dialysis

2005· article· en· W2077922374 on OpenAlexvenueno aff
G Bousquet

Bibliographic record

VenueHemodialysis International · 2005
Typearticle
Languageen
FieldHealth Professions
TopicCentral Venous Catheters and Hemodialysis
Canadian institutionsnot available
Fundersnot available
KeywordsMedicineCatheterBacteremiaSanitationHemodialysisCentral venous catheterInfection controlAntimicrobialSurgeryAsepsisDialysis catheterMicrobiologyPathologyAntibioticsBiology

Abstract

fetched live from OpenAlex

Purpose: Contamination of catheter hub connectors is known to cause catheter‐related blood stream infections in patients undergoing hemodialysis via central venous catheters (CVC). The effectiveness of cleansing the hub with an antimicrobial agent was assessed by culturing the surface of the hub following sanitation. Methods: The CVC hub connectors of 24 patients were sanitized using the standard hospital protocol of aseptically swabbing the connectors with a solution of bleach or Betadine, and then bathing the hub in sterile gauze soaked with the antimicrobial solution for 5 minutes. The exterior surface of the hub was then cultured for a broad spectrum of microorganisms. Patients were monitored for exit site infection, tunnel infection, and septicemia. In the laboratory, sterile hubs were inoculated with E. coli, staph. aureus neg., and yeast. Hubs were then immersed in Betadine for 5, 10, or 30 min. and cultures were taken. Results: Positive cultures were obtained from the hubs of 17 of the 24 patients. Seven (7) of the patients with positive results developed bacteremia from the cultured organism within 7 weeks. Positive cultures were obtained from 50% of inoculated lab samples after 5 min, 10% after 15 min, and 0% after 30 min. of immersion sanitation. Conclusions: The techniques for cleansing CVC hubs should be revisited.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.005
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.003
Threshold uncertainty score0.009

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.005
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0010.000
Open science0.0000.001
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0030.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.026
GPT teacher head0.358
Teacher spread0.332 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2005
Admission routes1
Has abstractyes

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