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Record W2078935291 · doi:10.1159/000217298

Comparison Of The Relative Efficacy And Safety Of Low Molecular Weight Heparin And Unfractionated Heparin For The Treatment Of Venous Thrombosis

2009· review· en· W2078935291 on OpenAlexaff
J. Hirsh

Bibliographic record

VenueHaemostasis · 2009
Typereview
Languageen
FieldMedicine
TopicVenous Thromboembolism Diagnosis and Management
Canadian institutionsJuravinski HospitalHamilton General Hospital
Fundersnot available
KeywordsMedicineHeparinThrombosisThrombusLow molecular weight heparinVenous thrombosisSurgeryIncidence (geometry)Randomized controlled trialMajor bleedingAnticoagulantAnesthesiaInternal medicine

Abstract

fetched live from OpenAlex

LMWH has been compared with unfractionated heparin in the treatment of venous thrombosis. The results of a pooled analysis studies of hospitalized patients showed a significant reduction of thrombus size, p < 0.001 and in the incidence of recurrent venous thromboembolism, p < 0.001 and of major bleeding p < 0.005 in patients treated with LMWH. The pooled mortality rate at long term follow-up was also found to be lower in LMWH group. Two large randomized trials have been completed in which LMWH was administered subcutaneously on an outpatient basis and compared with the standard approach of unfractionated heparin administered by continuous intravenous infusion in hospital. In both studies the efficacy, safety and mortality in the LMWH and heparin groups were similar.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.002
metaresearch head score (Gemma)0.004
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Meta-analysis · Consensus signal: none
GenreCandidate signal: Review · Consensus signal: Review
Teacher disagreement score0.004
Threshold uncertainty score0.009

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0020.004
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0040.001
Bibliometrics0.0030.003
Science and technology studies0.0000.000
Scholarly communication0.0010.001
Open science0.0010.000
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0030.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.071
GPT teacher head0.391
Teacher spread0.320 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designMeta-analysis
Domainnot available
GenreReview

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations20
Published2009
Admission routes1
Has abstractyes

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