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Record W2079547959 · doi:10.1159/000121870

Involvement of the Trigeminal Motor System in Brain Stem Self-Stimulation and Stimulation-Induced Behavior

2008· article· en· W2079547959 on OpenAlexafffund
Derek van der Kooy, Anthony G. Phillips

Bibliographic record

VenueBrain Behavior and Evolution · 2008
Typearticle
Languageen
FieldNeuroscience
TopicTranscranial Magnetic Stimulation Studies
Canadian institutionsUniversity of British Columbia
FundersKillam Trusts
KeywordsStimulationNeurosciencePonsTrigeminal nerveLocus coeruleusPsychologyAnatomyCentral nervous systemMedicine

Abstract

fetched live from OpenAlex

Anatomical and behavioral correlates of intracranial self-stimulation (ICSS) at sites in the pons suggest the involvement of the trigeminal motor system in brain stimulation reward. 90% of the electrodes terminating in or dorsal to the trigeminal motor nucleus supported ICSS. Stimulation through these ICSS electrodes was usually accompanied by a display of repetitive jaw movement in the period following brain stimulation. There appeared to be a close relation between post-stimulation jaw movement and ICSS. In the motor nucleus there was a positive linear relationship between current intensity and duration of jaw movement. Optimal current intensities for ICSS induced long periods of jaw movement. Extensive lesions of the dorsal pons which included the locus ceruleus had no effect on ICSS in the trigeminal motor system. Therefore it seems unlikely that ICSS in the trigeminal system is mediated by noradrenergic neurons located in the dorsal pontine area. These data suggest that a centripetal analysis of ICSS sites along pathways afferent to the trigeminal motor system may lead to a more complete description of the anatomical correlates of brain stimulation reward. The functional implications of a trigeminal reinforcement mechanism are discussed.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.002
Threshold uncertainty score0.005

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0020.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.051
GPT teacher head0.274
Teacher spread0.223 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations13
Published2008
Admission routes2
Has abstractyes

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