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Record W2080226291 · doi:10.1016/j.ejpain.2007.03.042

28 Workshop Summary: INVESTIGATION OF CENTRAL PAIN MECHANISMS IN HUMANS

2007· article· en· W2080226291 on OpenAlexaboutno aff
Nadine Attal

Bibliographic record

VenueEuropean Journal of Pain · 2007
Typearticle
Languageen
FieldMedicine
TopicMusculoskeletal pain and rehabilitation
Canadian institutionsnot available
Fundersnot available
KeywordsPsychologyNeuroscienceMedicine

Abstract

fetched live from OpenAlex

The pathophysiology of central pain syndromes is still poorly understood and their treatment remains a major challenge. Despite the development of several animal models of spinal cord injury pain, human studies are necessary to better link mechanisms to neuropathic symptoms and signs. Over the past years, several significant clinical studies have been devoted specifically to the mechanisms of central pain, particularly with regards to allodynia, in humans. These studies have used psychophysics, functional or morphological neuroimagery and electrophysiology. This workshop will outline the recent advances in our understanding of central pain mechanisms from human studies. Nanna Finnerup (Denmark) will present results of psychophysical and MRI studies obtained in spinal cord injury patients with at level and below level neuropathic pain, emphasizing the role of neuronal hyperexcitability at injury or higher level in spontaneous pain and allodynia. Roland Peyron (France) will present the contribution of functional imagery in the undestanding of the mechanisms of mechanical/cold allodynia and its relief after cortical stimulation in patients with central pain. Jonathan Dostrovsky (Canada) will present clinical and electrophysiological evidence from human studies supporting the role of the thalamus in central pain.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.001
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: Not applicable
GenreCandidate signal: Other · Consensus signal: Other
Teacher disagreement score0.054
Threshold uncertainty score0.180

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.001
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0000.001
Bibliometrics0.0000.000
Science and technology studies0.0010.000
Scholarly communication0.0010.001
Open science0.0010.002
Research integrity0.0030.002
Insufficient payload (model declined to judge)0.0540.023

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.017
GPT teacher head0.260
Teacher spread0.243 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designNot applicable
Domainnot available
GenreOther

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2007
Admission routes1
Has abstractyes

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