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Record W2080540798 · doi:10.1186/1471-2288-10-59

Dichotomization: 2 × 2 (×2 × 2 × 2...) categories: infinite possibilities

2010· article· en· W2080540798 on OpenAlexaff
Karyn Heavner, Carl V. Phillips, Igor Burstyn, Warren Hare

Bibliographic record

VenueBMC Medical Research Methodology · 2010
Typearticle
Languageen
FieldMedicine
TopicDiabetes, Cardiovascular Risks, and Lipoproteins
Canadian institutionsOkanagan University CollegeUniversity of British Columbia, Okanagan CampusUniversity of British ColumbiaUniversity of Alberta
Fundersnot available
KeywordsConfidence intervalOdds ratioCutoffOutlierStatisticsMedicineAssociation (psychology)EconometricsPsychologyMathematics

Abstract

fetched live from OpenAlex

BACKGROUND: Consumers of epidemiology may prefer to have one measure of risk arising from analysis of a 2-by-2 table. However, reporting a single measure of association, such as one odds ratio (OR) and 95% confidence interval, from a continuous exposure variable that was dichotomized withholds much potentially useful information. Results of this type of analysis are often reported for one such dichotomization, as if no other cutoffs were investigated or even possible. METHODS: This analysis demonstrates the effect of using different theory and data driven cutoffs on the relationship between body mass index and high cholesterol using National Health and Nutrition Examination Survey data. The recommended analytic approach, presentation of a graph of ORs for a range of cutoffs, is the focus of most of the results and discussion. RESULTS: These cutoff variations resulted in ORs between 1.1 and 1.9. This allows investigators to select a result that either strongly supports or provides negligible support for an association; a choice that is invisible to readers. The OR curve presents readers with more information about the exposure disease relationship than a single OR and 95% confidence interval. CONCLUSION: As well as offering results for additional cutoffs that may be of interest to readers, the OR curve provides an indication of whether the study focuses on a reasonable representation of the data or outlier results. It offers more information about trends in the association as the cutoff changes and the implications of random fluctuations than a single OR and 95% confidence interval.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.038
metaresearch head score (Gemma)0.191
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMetaresearch, Research integrity, Insufficient payload (model declined to judge)
Consensus categoriesMetaresearch
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Other design · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.943
Threshold uncertainty score0.999

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0380.191
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0010.001
Science and technology studies0.0000.002
Scholarly communication0.0000.000
Open science0.0010.000
Research integrity0.0010.003
Insufficient payload (model declined to judge)0.0080.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.276
GPT teacher head0.492
Teacher spread0.216 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; both teacher heads agree on what is shown here.

Study designOther design
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations26
Published2010
Admission routes1
Has abstractyes

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