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Record W2082333972 · doi:10.1177/108925320500900206

Applied Neuromonitoring and Improving CNS Outcomes

2005· review· en· W2082333972 on OpenAlex
John M. Murkin

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

affAt least one author lists a Canadian institution in the pinned OpenAlex snapshot.

Bibliographic record

VenueSeminars in Cardiothoracic and Vascular Anesthesia · 2005
Typereview
Languageen
FieldMedicine
TopicCardiac, Anesthesia and Surgical Outcomes
Canadian institutionsWestern University
Fundersnot available
KeywordsMedicineTranscranial DopplerPerioperativeCerebral perfusion pressureCardiac surgeryCardiopulmonary bypassMiddle cerebral arteryCardiologyEmbolizationStroke (engine)Cerebral autoregulationInternal medicineAnesthesiaCerebral blood flowSurgeryIschemiaBlood pressureAutoregulation

Abstract

fetched live from OpenAlex

Despite an overall decrease in perioperative morbidity and mortality, evidence of some degree of central nervous system dysfunction associated with coronary artery bypass graft (CABG) surgery-with or without cardiopulmonary bypass-has steadily mounted. From preoperative studies of CABG patients, it is apparent that over 50% of patients who present for cardiac surgery have evidence of either extracranial or intracranial atherosclerotic disease. Patient-specific factors thus have a fundamental impact on the risks of a brain injury developing after CABG surgery. Cerebral embolization and/or ischemic hypoperfusion are the most likely etiologic mechanisms for perioperative brain injury associated with cardiac surgery, and these factors are closely interrelated. Various monitoring techniques can decrease risk of intraoperative cerebral embolization and hypoperfusion and are associated with improved outcomes. Ultrasound guided aortic instrumentation (epiaortic scanning) can markedly decrease atheroembolic load and risk of stroke. Unrecognized sources of microgaseous emboli, including air entrainment from surgical purse string sutures and perfusionist interventions, can be identified and reduced by transcranial Doppler monitoring. Cerebral hypoperfusion from unrecognized cerebral venous obstruction, inadequate mean arterial pressure, or from hypocapnic cerebral alkalosis can be identified by multimodality neuromonitoring using regional cerebral oxygen saturation and transcranial Doppler. Overall patient outcomes can be improved, and hospital length of stay shortened, by applied neuromonitoring techniques.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Other design · Consensus signal: none
GenreCandidate signal: Review · Consensus signal: Review
Teacher disagreement score0.983
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.000
Meta-epidemiology (narrow)0.0010.001
Meta-epidemiology (broad)0.0060.002
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.025
GPT teacher head0.328
Teacher spread0.303 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it