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Record W2082456714 · doi:10.3899/jrheum.091301

Scurvy as the Presenting Illness of Whipple’s Disease Exacerbated by Treatment with Etanercept in a Patient with Ankylosing Spondylitis

2010· letter· en· W2082456714 on OpenAlex
Ihsane Hmamouchi, Valérie Costes, Bernard Combe, Jacques Morel

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

venuePublished in a venue whose home country is Canada.
no affNo Canadian affiliation: this work is invisible to an affiliation-only frame.
No Canadian affiliation. An affiliation-only frame, the usual design, would never have seen this work. It is one of the works that make the case for inverting the frame.

Bibliographic record

VenueThe Journal of Rheumatology · 2010
Typeletter
Languageen
FieldMedicine
TopicWhipple's Disease and Interleukins
Canadian institutionsnot available
FundersCentre National de la Recherche ScientifiqueInstitut National de la Santé et de la Recherche Médicale
KeywordsMedicineAnkylosing spondylitisEtanerceptSpondylitisErythrocyte sedimentation rateSurgeryInternal medicineGastroenterologyAbdominal painRheumatoid arthritis

Abstract

fetched live from OpenAlex

To the Editor: A 35-year-old man was diagnosed with ankylosing spondylitis (AS) in 2004. HLA-B27 typing was negative. He started therapy with etanercept 25 mg twice weekly subcutaneously in September 2008 because of highly active disease. Two months after starting etanercept, the condition was not improved. He was hospitalized because of sudden onset of a gingival nodule (Figure 1A), and purpura (Figure 1B), and a history of abdominal pain with 3 non-bloody stools per day, fatigue, early satiety, and a 6 kg weight loss during the preceding 4 months. Etanercept was then stopped. Figure 1. Clinical cutaneous manifestations associated with vitamin C deficiency before treatment (A, B) and reduction of these manifestations after 10 days of treatment (C, D). On examination at our institution, his temperature was 37.5°C, blood pressure 120/80 mm Hg, pulse 88 beats per minute, and weight 66 kg. The spleen edge was palpable 2 cm below the costovertebral margin. He had lower limb purpura, lower limb edema, and gingivitis. Results of abdominal and neurological examination were normal. Laboratory studies showed erythrocyte sedimentation rate (ESR) 82 … Address correspondence to Dr. Hmamouchi; E-mail: i.hmamouchi{at}yahoo.fr

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesResearch integrity
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: Not applicable
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.314
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0000.000
Science and technology studies0.0000.001
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.002
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.008
GPT teacher head0.239
Teacher spread0.230 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it