SPECT-Based Radiation Therapy and Transcatheter Arterial Chemoembolization for Unresectable Hepatocellular Carcinoma Sized 14 cm or Greater
Bibliographic record
Abstract
Purpose: To evaluate the feasibility of single photon emission computed tomography-based three-dimensional conformal radiotherapy (SPECT-B3DCRT) combined with transcatheter arterial chemoembolization (TACE) for large unresectable hepatocellular carcinoma. Methods: Twelve patients with unresectable hepatocellular carcinoma (HCC) sized 14 cm or greater underwent SPECT using Tc-99m-galactosyl human serum albumin before 3DCRT to explore the optimal irradiation beam angle to cover the clinical target volume (CTV) to a total dose of 45 Gy/18 fractions while preserving functional liver volume (FLV). The TACE was scheduled within two months after completion of 3DCRT. Results: Local control rate was 78.6% at 2 years. Median over-all survival was 10.1 months and the survival rate at 1 and 2 years was 41.7 and 33.3%, respectively. Conclusions: SPECT-B3DCRT combined with TACE appears to be tolerable and effective for patients with HCC sized 14 cm or greater in terms of local control and survival.
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.001 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.001 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.002 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".