Blindness or Agnosia: Review of Posterior Cortical Atrophy and a Difficult Case
Bibliographic record
Abstract
The Objective was to brie fly review the rare condition Posterior Cortical Atrophy (PCA) and demonstrate a difficult case suffering from both visual disturbances due to glaucoma and visual agnosia due to PCA. The short review was made by Pub Med search including “Posterior Cortical Atrophy” and the reference lists from the obtained articles were scrutinized for relevant literature not retrieved from PubMed. PCA is a slowly progressing neurodegenerative disorder that is very disabling due to disturbances of higher visual functions, although memory might be relatively preserved until late in the course. Some previous authors have underscored, that to diagnose a patient with PCA one must rule out that the patient is suffering from an eye disease. We demonstrate a difficult case suffering from both glaucoma and PCA. The diagnostic characteristics for PCA are described, and neuroimaging including positron emission tomography (PET) with the amyloid binding ligand (11C) Pittsburgh compound B (PiB), and results from treatment of PCA are presented. Caution should be advised when patients with impaired visual acuity develop signs of cognitive dysfunction, and a full neuropsychological examination should be performed whenever there is doubt of the significance of visual impairment and impaired visuospatial functions. doi:10.4021/jnr91w
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How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.001 | 0.002 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.001 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.001 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".