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What metaphor for the aging brain?

2007· letter· en· W2085694667 on OpenAlexaff
Kenneth Rockwood

Bibliographic record

VenueNeurology · 2007
Typeletter
Languageen
FieldMedicine
TopicDementia and Cognitive Impairment Research
Canadian institutionsDalhousie University
Fundersnot available
KeywordsCognitionPsychologyCognitive declineMetaphorDiseaseCognitive psychologyMedicineNeuroscienceDementiaPathologyLinguistics

Abstract

fetched live from OpenAlex

Most of us do not often think about how we think, and that's probably just as well. Our language can circle around itself, often taking us up blind alleys, or into a complexity that is as irredeemable as it is irrelevant to daily practice. But sometimes we must give mind to our metaphors. For a long time we have thought of the brain in old age as an innocent bystander. It sometimes gets bruised and sometimes beaten up, but it's not as though it can do a lot about it. Other metaphors have competed, including the brain as repository, coming to old age with assets that inexorably dwindle, until they meet a threshold, after which disease occurs. In this issue, Wilson and colleagues1 report that people who habitually engage in high levels of cognitive activity showed less cognitive decline—and less often had Alzheimer disease (AD)—than did people with less cognitively activating routines. The Rush Memory and Aging Project is a prospective clinicopathologic study, whose 931 participants have agreed to annual examinations and brain autopsy. Its high retention rate (93.5% of people enrolled for more than 1 year average were followed 3.5 times on average) and detailed evaluations provide insights into the …

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.009
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: Not applicable
GenreCandidate signal: Commentary · Consensus signal: Commentary
Teacher disagreement score0.015
Threshold uncertainty score0.024

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.009
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0010.000
Science and technology studies0.0030.004
Scholarly communication0.0020.007
Open science0.0010.001
Research integrity0.0150.016
Insufficient payload (model declined to judge)0.0050.004

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.038
GPT teacher head0.354
Teacher spread0.316 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designNot applicable
Domainnot available
GenreCommentary

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations4
Published2007
Admission routes1
Has abstractyes

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