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Record W2086025365 · doi:10.1139/z04-008

Stress protein expression is related to tail loss in two species of iguanid lizards

2004· article· en· W2086025365 on OpenAlexvenueno aff
Santiago Merino, M. Carmen Blázquez, Javier Martı́nez, Ricardo Rodríguez‐Estrella

Bibliographic record

VenueCanadian Journal of Zoology · 2004
Typearticle
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicHeat shock proteins research
Canadian institutionsnot available
FundersCentro de Investigaciones Biológicas del NoroesteConsejo Nacional de Ciencia y Tecnología
KeywordsBiologyHSP60Hsp70Heat shock proteinWestern blotAntiserumZoologyImmunologyGeneticsAntibodyGene

Abstract

fetched live from OpenAlex

During the spring of 1999, two species of iguanid lizards were captured in southern Baja California peninsula, Mexico. Blood was obtained from the tail to check for the presence of blood parasites in smears and stress proteins in cells. Levels of HSP70- and HSP60-like proteins from Sceloporus licki Van Denburgh, 1895 and Petrosaurus thalassinus (Cope, 1863) were analyzed with Western blot using antisera to human HSP60 and bovine HSP70. The potential effects of sex, tail regeneration, and haemoparasites on the expression of these proteins were also investigated. Both species differ significantly in stress protein levels and infection by haemoparasites. Petrosaurus thalassinus show the lower stress protein levels and the higher proportion of infection. Although blood parasites apparently affect the condition of P. thalassinus, stress protein levels are not significantly related with haemoparasites or condition. However, S. licki lizards showing tail regeneration have lower levels of HSP60-like protein. A negative relationship exists between the length of the regenerated part of the tail and the level of HSP60-like protein for S. licki. Based on what is known of the function of HSP60, down-regulation of the protein in blood cells may be linked to reallocation of energies to other tissues more active metabolically.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.008
Threshold uncertainty score0.016

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0010.000
Science and technology studies0.0010.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.013
GPT teacher head0.284
Teacher spread0.271 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations6
Published2004
Admission routes1
Has abstractyes

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