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Record W2086142421 · doi:10.1080/15321810701454904

<i>Salmonella enterica</i> Serotype Urbana Interference with Brucellosis Serology

2007· article· en· W2086142421 on OpenAlexaff
K. Nielsen, Phillip D. Smith, Yu Wang, G. Halbert

Bibliographic record

VenueJournal of Immunoassay and Immunochemistry · 2007
Typearticle
Languageen
FieldVeterinary
TopicBrucella: diagnosis, epidemiology, treatment
Canadian institutionsCanadian Food Inspection Agency
Fundersnot available
KeywordsDirect agglutination testSerologyComplement fixation testSerotypeMicrobiologyAntigenYersinia enterocoliticaBiologyBrucellosisSalmonella entericaBrucellaImmunoassayVirologyAntibodySalmonellaImmunologyBacteria

Abstract

fetched live from OpenAlex

Sheep were immunized with killed Salmonella enterica serotype Urbana cells and their sera were tested in various serological tests for antibody to Brucella sp., Yersinia enterocolitica O:9 and Escherichia coli O:157 H:7. Of the eight sheep, all gave a positive agglutination reaction in the brucellosis buffered antigen plate agglutination test (BPAT), seven gave positive brucellosis standard tube agglutination test (TAT) and complement fixation test (CFT) results and four gave slightly positive reactions in a competitive enzyme immunoassay (CELISA). Seven sera were negative in an indirect enzyme immunoassay (IELISA-SLPS) using B. abortus smooth lipopolysaccharide (SLPS) antigen and all were negative in a fluorescence polarization assay (FPA-OPS) using B. abortus O-polysaccharide antigen. Two sheep gave a slight positive reaction in an IELISA using Brucella rough lipopolysaccharide antigen (IELISA-RLPS) and four sheep were slightly positive in an FPA using Brucella LPS core antigen (FPA-CORE). All sheep had high antibody responses to S. enterica serotype Urbana, Y. and E. coli O:157 and 7 were positive for antibody to Y. enterocolitica O:9 when tested by IELISA. The sheep were negative when tested in the FPA using OPS from Y. enterocolitica O:9 but all were strongly positive in the FPA using OPS from E. coli O:157 while seven sheep had titers to S. enterica serotype Urbana. The impact on diagnostic serology for brucellosis is discussed.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.239
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0010.000
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.029
GPT teacher head0.298
Teacher spread0.270 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations31
Published2007
Admission routes1
Has abstractyes

Explore more

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