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Evaluating Implants in Orthopaedic Trials: Tips for Conducting Research

2013· article· en· W2086636112 on OpenAlexaff
Simrit Bains, Beate Hanson, Mohit Bhandari

Bibliographic record

VenueJournal of Long-Term Effects of Medical Implants · 2013
Typearticle
Languageen
FieldDecision Sciences
TopicMeta-analysis and systematic reviews
Canadian institutionsMcMaster UniversityHamilton General HospitalWestern University
Fundersnot available
KeywordsBlindingObservational studyProtocol (science)Randomized controlled trialRandomizationMedical physicsMedicineClinical trialQuality (philosophy)Research designAlternative medicinePhysical therapySurgeryPathologyMathematics

Abstract

fetched live from OpenAlex

The availability of quality research on orthopaedic implants is important for orthopaedic clinical practice, though in many cases such research is deficient in the literature. Randomized trials are dwarfed in number by observational studies which, though also valuable, do not provide the same validity of evidence. This is partly due to the unique challenges faced by orthopaedic clinicians when attempting to conduct randomized trials in areas such as randomization, blinding, and follow-up. These challenges can be addressed with the use of techniques such as expertise-based randomization, assessment that is objective and independent, and implementation of a protocol for consistent follow-up before the study is underway. Although they do not eliminate all of the hurdles faced in implant evaluation trials, the tips outlined in this article have the potential to significantly ease the burdens of conducting high-quality research.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.583
metaresearch head score (Gemma)0.607
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMetaresearch, Insufficient payload (model declined to judge)
Consensus categoriesMetaresearch
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.794
Threshold uncertainty score0.997

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.5830.607
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0060.002
Bibliometrics0.0010.001
Science and technology studies0.0000.000
Scholarly communication0.0000.001
Open science0.0030.000
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0040.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.940
GPT teacher head0.708
Teacher spread0.232 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; both teacher heads agree on what is shown here.

Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2013
Admission routes1
Has abstractyes

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