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Record W2089672316 · doi:10.1002/cne.20269

Class I and class II ganglion cells of rabbit retina: Quantitative analysis of dendritic branching patterns

2004· article· en· W2089672316 on OpenAlexaff
Edward V. Famiglietti

Bibliographic record

VenueThe Journal of Comparative Neurology · 2004
Typearticle
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicRetinal Development and Disorders
Canadian institutionsUniversity of Calgary
FundersNational Eye InstituteNational Institutes of Health
KeywordsBiologyRetinaRabbit (cipher)GanglionBranching (polymer chemistry)NeuroscienceGiant retinal ganglion cellsBistratified cellClass (philosophy)Cell biologyRetinal ganglion cellArtificial intelligenceComputer science

Abstract

fetched live from OpenAlex

Class I and class II ganglion cells, distinguished from one another in a companion paper, were analyzed in regard to their dendritic branching patterns by determination of: 1) mean "branching density" (BD), 2) "radial branching frequency" (RBF), and 3) "branch length distributions" (BLDs; Famiglietti [ 1992a] J Comp Neurol 324:295-321). Branching density of class II cells exceeded that of class I cells by a factor of two, when compared at the same retinal location, but declined with increasing distance from the visual streak (dvs). A one-bin difference in RBF between class I and class II cells was not statistically significant. BLDs are scatter-plots of individual preterminal and terminal branch lengths versus the distances of their origins from the soma. The parameters mp and mt, the slopes of regression lines fitted to the preterminal and terminal BLDs, respectively, were determined; mp, but not mt, was relatively independent of dvs, and was used empirically to determine a boundary value, mp = +5.0, separating "radiate" from "tufted" dendritic branching. Similarity of class I (mp = +8.6 +/- 4.6) and class II (mp = +1.4 +/- 5.2) cells did not allow a statistically significant separation of the two classes, based upon branching pattern alone; however, mp together with mt easily separated class I cells (mt = -17.8 +/- 10.0) and particularly "tufted" class II cells (mt = -16 +/- 9.3) from "tufted" class III.1 ganglion cells (Famiglietti, 1992a), with their qualitatively different, more regular branching (mp = +2.1 +/- 0.85; mt = +0.65 +/- 4.9).

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.187
Threshold uncertainty score0.340

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.016
GPT teacher head0.276
Teacher spread0.260 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations10
Published2004
Admission routes1
Has abstractyes

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