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Record W2089923076 · doi:10.1021/ja048911m

Me<sub>2</sub>AlCH<sub>2</sub>PMe<sub>2</sub>: A New, Bifunctional Cocatalyst for the Ni(II)-Catalyzed Oligomerization of PhSiH<sub>3</sub>

2004· article· en· W2089923076 on OpenAlexaff
Frédéric‐Georges Fontaine, Davit Zargarian

Bibliographic record

VenueJournal of the American Chemical Society · 2004
Typearticle
Languageen
FieldChemistry
TopicOrganoboron and organosilicon chemistry
Canadian institutionsUniversité de Montréal
Fundersnot available
KeywordsChemistryBifunctionalMoietyNucleophileCatalysisQuinuclidineMethylaluminoxaneReagentMonomerMedicinal chemistryLewis acids and basesStereochemistryOrganic chemistryPolymerizationMetallocene

Abstract

fetched live from OpenAlex

The role of methylaluminoxane (MAO) in the Ni-catalyzed dehydrogenative homologation of PhSiH3 has been investigated with a view to designing new cocatalysts possessing well-defined chemical compositions and structures. These studies show that species such as the bifunctional reagent (Me2PCH2AlMe2)2, 3, should act as co-catalyst for the Si-Si bond formation reactions. Thus, it was found that the combination of (1-Me-indenyl)Ni(PPh3)Me, 2a, and 3 (Ni/Al ratio of 1:1) converts PhSiH3 to cyclic oligomers (PhSiH)n with a turnover frequency (TOF) of >500 h(-1), 50 times faster than with 2a alone. Detailed NMR studies have indicated that this acceleration is due to the formation of the intermediate (1-Me-indenyl)Ni(Me)(Me2PCH2AlMe2), 4. Coordination of the PMe2 moiety in this complex to the Ni center allows the tethered AlMe2 moiety to interact with the Ni-Me moiety in such a way that promotes fairly slow Al-Me/Ni-CD3 exchange (t(1/2) ca. 12 h) but accelerates the Si-H bond activation and Si-Si bond formation reactions. The catalysis promoted by 2a/3 proceeds even faster in the presence of NEt3 or THF (TOF > 1600 h(-1)), because these Lewis bases favor the monomeric form of 3, which in turn favors the formation of 4. On the other hand, the much more nucleophilic base quinuclidine suppresses the catalysis (TOF < 300 h(-1)) by hindering the Ni.R.Al interactions. These observations point to an emerging strategy for using bifunctional reagents such as 3 to place geometrically constrained Lewis acid moieties adjacent to metal centers, thereby activating certain metal-ligand bonds.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.001
Threshold uncertainty score0.003

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.008
GPT teacher head0.221
Teacher spread0.213 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations114
Published2004
Admission routes1
Has abstractyes

Explore more

Same venueJournal of the American Chemical SocietySame topicOrganoboron and organosilicon chemistryFrench-language works237,207